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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGHMBP2
All Species:
20.61
Human Site:
S749
Identified Species:
50.37
UniProt:
P38935
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P38935
NP_002171.2
993
109123
S749
M
Q
L
E
F
P
P
S
L
N
S
H
D
R
L
Chimpanzee
Pan troglodytes
XP_508608
997
109427
S749
M
Q
L
E
F
P
P
S
L
N
S
H
D
R
L
Rhesus Macaque
Macaca mulatta
XP_001117732
920
100973
A687
Q
E
G
G
R
E
S
A
A
A
A
R
Q
G
R
Dog
Lupus familis
XP_540807
1010
110075
S754
T
Q
L
E
F
P
P
S
L
N
S
H
D
R
M
Cat
Felis silvestris
Mouse
Mus musculus
P40694
993
109448
S747
S
Q
L
E
F
P
T
S
L
S
S
H
D
R
L
Rat
Rattus norvegicus
Q9EQN5
988
108422
S747
A
Q
L
E
F
P
T
S
L
S
S
H
D
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038365
997
110867
T743
T
E
L
E
F
P
S
T
L
N
S
H
D
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795848
413
45058
A191
E
S
V
E
F
F
N
A
N
L
N
E
S
Q
R
Poplar Tree
Populus trichocarpa
XP_002308965
647
71270
E425
G
L
G
R
T
L
F
E
R
L
T
D
L
Y
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565299
639
70832
F417
K
G
L
G
R
T
L
F
E
R
L
A
D
L
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
88.5
81
N.A.
76.7
77.9
N.A.
N.A.
N.A.
N.A.
56.7
N.A.
N.A.
N.A.
N.A.
23.4
Protein Similarity:
100
98.9
89.8
87.7
N.A.
85.1
85.5
N.A.
N.A.
N.A.
N.A.
72.3
N.A.
N.A.
N.A.
N.A.
32.1
P-Site Identity:
100
100
0
86.6
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
20
93.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
31
N.A.
N.A.
30.2
N.A.
N.A.
Protein Similarity:
44
N.A.
N.A.
43.9
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
20
10
10
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
70
0
0
% D
% Glu:
10
20
0
70
0
10
0
10
10
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
70
10
10
10
0
0
0
0
0
0
0
% F
% Gly:
10
10
20
20
0
0
0
0
0
0
0
0
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
70
0
0
10
10
0
60
20
10
0
10
10
50
% L
% Met:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
10
0
10
40
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
60
30
0
0
0
0
0
0
0
0
% P
% Gln:
10
50
0
0
0
0
0
0
0
0
0
0
10
10
0
% Q
% Arg:
0
0
0
10
20
0
0
0
10
10
0
10
0
60
20
% R
% Ser:
10
10
0
0
0
0
20
50
0
20
60
0
10
0
0
% S
% Thr:
20
0
0
0
10
10
20
10
0
0
10
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _