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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGHMBP2
All Species:
8.48
Human Site:
S677
Identified Species:
20.74
UniProt:
P38935
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P38935
NP_002171.2
993
109123
S677
A
T
S
T
R
T
G
S
Q
R
Q
E
G
G
Q
Chimpanzee
Pan troglodytes
XP_508608
997
109427
S677
A
T
S
T
R
T
G
S
Q
R
Q
E
G
G
Q
Rhesus Macaque
Macaca mulatta
XP_001117732
920
100973
L626
N
H
A
F
L
K
T
L
V
E
Y
F
T
Q
H
Dog
Lupus familis
XP_540807
1010
110075
P676
A
A
L
S
R
K
P
P
G
S
R
P
Q
E
G
Cat
Felis silvestris
Mouse
Mus musculus
P40694
993
109448
S676
T
S
I
R
K
P
A
S
D
Q
E
S
G
Q
E
Rat
Rattus norvegicus
Q9EQN5
988
108422
S676
T
S
V
R
K
P
A
S
A
Q
E
S
R
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038365
997
110867
K675
Q
K
T
K
K
Q
D
K
K
P
E
Q
E
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795848
413
45058
G130
N
V
E
G
I
A
R
G
H
D
D
T
Y
K
L
Poplar Tree
Populus trichocarpa
XP_002308965
647
71270
K364
L
T
G
A
F
S
H
K
L
N
T
T
S
F
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565299
639
70832
R356
T
L
T
G
A
L
T
R
K
L
D
N
R
T
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
88.5
81
N.A.
76.7
77.9
N.A.
N.A.
N.A.
N.A.
56.7
N.A.
N.A.
N.A.
N.A.
23.4
Protein Similarity:
100
98.9
89.8
87.7
N.A.
85.1
85.5
N.A.
N.A.
N.A.
N.A.
72.3
N.A.
N.A.
N.A.
N.A.
32.1
P-Site Identity:
100
100
0
13.3
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
6.6
26.6
N.A.
46.6
40
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
31
N.A.
N.A.
30.2
N.A.
N.A.
Protein Similarity:
44
N.A.
N.A.
43.9
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
10
10
10
10
10
20
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
10
10
20
0
0
0
10
% D
% Glu:
0
0
10
0
0
0
0
0
0
10
30
20
10
10
20
% E
% Phe:
0
0
0
10
10
0
0
0
0
0
0
10
0
10
10
% F
% Gly:
0
0
10
20
0
0
20
10
10
0
0
0
30
20
10
% G
% His:
0
10
0
0
0
0
10
0
10
0
0
0
0
10
10
% H
% Ile:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
30
20
0
20
20
0
0
0
0
10
10
% K
% Leu:
10
10
10
0
10
10
0
10
10
10
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
20
10
10
0
10
0
10
0
0
0
% P
% Gln:
10
0
0
0
0
10
0
0
20
20
20
10
10
30
20
% Q
% Arg:
0
0
0
20
30
0
10
10
0
20
10
0
20
0
0
% R
% Ser:
0
20
20
10
0
10
0
40
0
10
0
20
10
0
0
% S
% Thr:
30
30
20
20
0
20
20
0
0
0
10
20
10
10
0
% T
% Val:
0
10
10
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _