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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGHMBP2
All Species:
22.42
Human Site:
S578
Identified Species:
54.81
UniProt:
P38935
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P38935
NP_002171.2
993
109123
S578
E
K
E
A
V
I
L
S
F
V
R
S
N
R
K
Chimpanzee
Pan troglodytes
XP_508608
997
109427
S578
E
K
E
A
V
I
L
S
F
V
R
S
N
R
K
Rhesus Macaque
Macaca mulatta
XP_001117732
920
100973
A532
L
V
D
A
G
V
P
A
R
D
V
A
V
V
S
Dog
Lupus familis
XP_540807
1010
110075
S577
E
K
E
A
V
V
L
S
F
V
R
S
N
R
K
Cat
Felis silvestris
Mouse
Mus musculus
P40694
993
109448
T577
E
K
E
A
V
L
L
T
F
V
R
S
N
R
K
Rat
Rattus norvegicus
Q9EQN5
988
108422
T577
E
K
E
A
V
I
L
T
F
V
R
S
N
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038365
997
110867
S576
E
K
E
A
V
V
L
S
L
V
R
S
N
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795848
413
45058
R36
L
L
G
K
L
S
V
R
E
L
E
R
R
G
V
Poplar Tree
Populus trichocarpa
XP_002308965
647
71270
L270
H
R
V
K
L
V
R
L
G
H
P
A
R
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565299
639
70832
R262
P
H
K
V
K
L
V
R
V
G
H
P
A
R
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
88.5
81
N.A.
76.7
77.9
N.A.
N.A.
N.A.
N.A.
56.7
N.A.
N.A.
N.A.
N.A.
23.4
Protein Similarity:
100
98.9
89.8
87.7
N.A.
85.1
85.5
N.A.
N.A.
N.A.
N.A.
72.3
N.A.
N.A.
N.A.
N.A.
32.1
P-Site Identity:
100
100
6.6
93.3
N.A.
86.6
93.3
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
31
N.A.
N.A.
30.2
N.A.
N.A.
Protein Similarity:
44
N.A.
N.A.
43.9
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
70
0
0
0
10
0
0
0
20
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
60
0
60
0
0
0
0
0
10
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
0
0
0
10
10
0
0
0
10
0
% G
% His:
10
10
0
0
0
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
60
10
20
10
0
0
0
0
0
0
0
0
0
60
% K
% Leu:
20
10
0
0
20
20
60
10
10
10
0
0
0
10
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% N
% Pro:
10
0
0
0
0
0
10
0
0
0
10
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
10
20
10
0
60
10
20
70
0
% R
% Ser:
0
0
0
0
0
10
0
40
0
0
0
60
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% T
% Val:
0
10
10
10
60
40
20
0
10
60
10
0
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _