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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V1A All Species: 60.3
Human Site: S350 Identified Species: 88.44
UniProt: P38606 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P38606 NP_001681.2 617 68304 S350 H V S M M A D S T S R W A E A
Chimpanzee Pan troglodytes XP_516655 617 68339 S350 H V S M M A D S T S R W A E A
Rhesus Macaque Macaca mulatta XP_001106889 617 68313 S350 H V S M M A D S T S R W A E A
Dog Lupus familis XP_545103 618 68384 S351 H V S M M A D S T S R W A E A
Cat Felis silvestris
Mouse Mus musculus P50516 617 68308 S350 H V S M M A D S T S R W A E A
Rat Rattus norvegicus NP_001101788 617 68247 S350 H V S M M A D S T S R W A E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507849 617 68305 S350 H V S M M A D S T S R W A E A
Chicken Gallus gallus Q90647 617 68458 S350 H V S M M A D S T S R W A E A
Frog Xenopus laevis NP_001089571 617 68506 S350 H V S M M A D S T S R W A E A
Zebra Danio Brachydanio rerio XP_002666686 617 68360 S350 N V S M M A D S T S R W A E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27331 614 68283 S347 N V S M M A D S T S R W A E A
Honey Bee Apis mellifera XP_623495 616 68354 S349 N V S M M A D S T S R W A E A
Nematode Worm Caenorhab. elegans Q9XW92 606 66441 A346 S T S R W A E A L R E I S G R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P49087 561 61933 Y315 E M P A D S G Y P A Y L A A R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23654 623 68794 S353 N V S M M A D S T S R W A E A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P11592 607 67103 S346 N V A M M A D S S S R W A E A
Conservation
Percent
Protein Identity: 100 99.5 99.8 98.5 N.A. 98 97.7 N.A. 96.2 95.3 93.1 93.1 N.A. 83.3 83.1 79.9 N.A.
Protein Similarity: 100 99.6 100 99.6 N.A. 99.3 99.1 N.A. 98.8 98 97.5 96.9 N.A. 91.9 93 89.1 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 93.3 93.3 13.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 100 100 33.3 N.A.
Percent
Protein Identity: N.A. 63.5 N.A. 68.5 N.A. 63.5
Protein Similarity: N.A. 76.5 N.A. 80.7 N.A. 78.9
P-Site Identity: N.A. 6.6 N.A. 93.3 N.A. 80
P-Site Similarity: N.A. 26.6 N.A. 100 N.A. 100
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 94 0 7 0 7 0 0 94 7 88 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 88 0 0 0 0 0 0 0 0 % D
% Glu: 7 0 0 0 0 0 7 0 0 0 7 0 0 88 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % G
% His: 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 7 0 0 7 0 0 0 % L
% Met: 0 7 0 88 88 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 7 0 0 0 0 0 7 88 0 0 0 13 % R
% Ser: 7 0 88 0 0 7 0 88 7 88 0 0 7 0 0 % S
% Thr: 0 7 0 0 0 0 0 0 82 0 0 0 0 0 0 % T
% Val: 0 88 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 7 0 0 0 0 0 0 88 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _