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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETFB
All Species:
29.39
Human Site:
S220
Identified Species:
53.89
UniProt:
P38117
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P38117
NP_001014763.1
255
27844
S220
D
L
G
V
D
L
T
S
K
L
S
V
I
S
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116312
255
27716
S220
D
L
G
V
D
L
T
S
K
L
S
V
I
S
V
Dog
Lupus familis
XP_533603
255
27727
S220
D
L
G
V
D
L
T
S
K
L
S
I
V
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCW4
255
27605
S220
D
L
G
V
D
L
T
S
K
V
S
V
I
S
V
Rat
Rattus norvegicus
Q68FU3
255
27669
S220
D
L
G
V
D
L
T
S
K
V
S
V
I
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520393
213
23066
V173
V
D
G
G
L
E
T
V
R
L
K
L
P
S
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080044
254
27496
S219
D
L
G
V
D
I
T
S
R
I
R
I
L
S
V
Zebra Danio
Brachydanio rerio
NP_998163
254
27507
S219
D
L
G
V
D
V
S
S
R
L
E
V
L
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651727
253
27199
P218
D
L
G
V
D
T
S
P
R
I
E
V
I
S
V
Honey Bee
Apis mellifera
XP_393789
253
27563
A218
D
L
G
V
D
T
T
A
R
I
E
I
L
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792626
434
49007
P219
D
L
G
V
D
V
S
P
R
V
E
T
V
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LSW8
251
27382
S215
D
L
K
V
D
I
K
S
D
I
E
I
L
E
V
Baker's Yeast
Sacchar. cerevisiae
P42940
261
28740
P226
F
P
E
I
N
I
E
P
Q
L
K
I
V
S
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
94.5
N.A.
92.1
92.9
N.A.
72.1
N.A.
80.3
78
N.A.
69.8
65.4
N.A.
44.2
Protein Similarity:
100
N.A.
99.2
98.4
N.A.
97.6
96.8
N.A.
76.8
N.A.
90.1
88.2
N.A.
80
81.1
N.A.
51.6
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
93.3
N.A.
33.3
N.A.
60
60
N.A.
60
53.3
N.A.
40
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
46.6
N.A.
93.3
86.6
N.A.
80
86.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
60.3
47.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
75.6
67.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
85
8
0
0
85
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
8
8
0
0
0
39
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
85
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
24
0
0
0
31
0
39
39
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
39
0
16
0
0
8
0
% K
% Leu:
0
85
0
0
8
39
0
0
0
47
0
8
31
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
24
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
47
0
8
0
0
8
0
% R
% Ser:
0
0
0
0
0
0
24
62
0
0
39
0
0
77
0
% S
% Thr:
0
0
0
0
0
16
62
0
0
0
0
8
0
0
0
% T
% Val:
8
0
0
85
0
16
0
8
0
24
0
47
24
0
93
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _