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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPL4
All Species:
34.85
Human Site:
S290
Identified Species:
54.76
UniProt:
P36578
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36578
NP_000959.2
427
47697
S290
K
M
I
N
T
D
L
S
R
I
L
K
S
P
E
Chimpanzee
Pan troglodytes
XP_001174724
477
52941
S340
K
M
I
N
T
D
L
S
R
I
L
K
S
P
E
Rhesus Macaque
Macaca mulatta
XP_001110697
427
47670
S290
K
M
I
N
T
D
L
S
R
I
L
K
S
P
E
Dog
Lupus familis
XP_535522
422
47287
S290
K
M
L
N
T
D
L
S
R
I
L
K
S
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8E6
419
47135
S290
K
M
M
N
T
D
L
S
R
I
L
K
S
P
E
Rat
Rattus norvegicus
P50878
421
47238
S290
K
M
M
N
T
D
L
S
R
I
L
K
S
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007480
421
46731
G290
K
M
T
N
T
D
L
G
R
I
L
R
S
Q
E
Frog
Xenopus laevis
P02385
401
45407
T294
K
M
T
N
T
D
L
T
R
I
L
K
S
Q
E
Zebra Danio
Brachydanio rerio
NP_998272
375
42534
N290
K
M
S
I
T
D
L
N
R
I
I
K
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09180
401
45007
S293
K
M
A
N
T
D
L
S
R
L
L
K
S
E
E
Honey Bee
Apis mellifera
XP_392071
429
48348
S292
K
M
M
N
T
D
L
S
R
L
L
K
S
Q
E
Nematode Worm
Caenorhab. elegans
O02056
345
38641
G264
K
K
L
D
T
I
Y
G
T
T
V
A
N
S
S
Sea Urchin
Strong. purpuratus
XP_783473
385
43329
R292
K
M
T
N
T
D
L
R
R
L
L
R
S
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SF40
406
44684
A296
K
M
V
N
A
D
L
A
R
I
I
N
S
D
E
Baker's Yeast
Sacchar. cerevisiae
P49626
362
39044
G273
T
V
A
S
S
K
V
G
Y
T
L
P
S
H
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
99.5
95.5
N.A.
91.5
91.3
N.A.
N.A.
81.5
78.4
73.5
N.A.
61.3
63.1
49.1
64.4
Protein Similarity:
100
89.5
99.7
97.4
N.A.
92.2
92.2
N.A.
N.A.
87.3
85.2
82.1
N.A.
74.2
77.6
63.9
75.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
73.3
80
66.6
N.A.
80
80
13.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
80
86.6
80
N.A.
86.6
93.3
40
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
53.6
51
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69
65.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
0
7
0
0
7
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
87
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
87
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
20
7
0
7
0
0
0
67
14
0
0
0
7
% I
% Lys:
94
7
0
0
0
7
0
0
0
0
0
67
0
0
0
% K
% Leu:
0
0
14
0
0
0
87
0
0
20
80
0
0
0
0
% L
% Met:
0
87
20
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
80
0
0
0
7
0
0
0
7
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
40
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
27
0
% Q
% Arg:
0
0
0
0
0
0
0
7
87
0
0
14
0
0
0
% R
% Ser:
0
0
7
7
7
0
0
54
0
0
0
0
94
7
7
% S
% Thr:
7
0
20
0
87
0
0
7
7
14
0
0
0
0
0
% T
% Val:
0
7
7
0
0
0
7
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _