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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V1E1
All Species:
14.85
Human Site:
S171
Identified Species:
25.13
UniProt:
P36543
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36543
NP_001687.1
226
26145
S171
D
V
Q
I
D
Q
E
S
Y
L
P
E
D
I
A
Chimpanzee
Pan troglodytes
XP_001163440
227
26153
S172
D
V
Q
I
D
Q
E
S
Y
L
P
E
D
I
A
Rhesus Macaque
Macaca mulatta
XP_001113068
226
26042
A171
E
V
Q
I
D
Q
E
A
Y
L
A
V
N
A
A
Dog
Lupus familis
XP_534937
226
26155
S171
D
V
Q
I
D
Q
E
S
Y
L
P
E
E
I
A
Cat
Felis silvestris
Mouse
Mus musculus
P50518
226
26139
A171
D
V
Q
I
D
Q
E
A
Y
L
P
E
E
I
A
Rat
Rattus norvegicus
Q6PCU2
226
26110
A171
D
V
Q
I
D
L
E
A
Y
L
P
E
D
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006246
226
26100
N171
D
I
H
I
D
Q
D
N
F
L
P
E
E
I
A
Frog
Xenopus laevis
NP_001079767
226
25885
T171
E
V
I
I
D
Q
E
T
H
L
T
P
E
I
A
Zebra Danio
Brachydanio rerio
NP_775361
226
25892
N171
E
V
R
I
D
Q
D
N
F
L
S
P
E
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54611
226
26064
D171
E
L
F
I
D
E
K
D
F
L
S
A
D
T
C
Honey Bee
Apis mellifera
XP_625098
226
26115
N171
T
I
K
V
D
Q
D
N
F
L
P
S
D
S
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39258
230
26041
D180
P
P
P
P
K
S
N
D
P
H
G
L
H
C
S
Baker's Yeast
Sacchar. cerevisiae
P22203
233
26453
Y178
E
I
V
I
S
N
D
Y
L
N
K
D
L
V
S
Red Bread Mold
Neurospora crassa
Q01278
230
25730
N175
K
A
T
I
D
A
E
N
P
V
P
E
G
S
A
Conservation
Percent
Protein Identity:
100
85.9
77.4
99.1
N.A.
98.6
98.6
N.A.
N.A.
88
83.1
77.4
N.A.
63.2
63.2
N.A.
N.A.
Protein Similarity:
100
88.5
87.6
99.5
N.A.
99.5
99.1
N.A.
N.A.
95.5
93.8
90.2
N.A.
81.8
81.4
N.A.
N.A.
P-Site Identity:
100
100
60
93.3
N.A.
86.6
86.6
N.A.
N.A.
60
53.3
40
N.A.
26.6
33.3
N.A.
N.A.
P-Site Similarity:
100
100
80
100
N.A.
100
93.3
N.A.
N.A.
93.3
80
86.6
N.A.
60
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.8
33
42.1
Protein Similarity:
N.A.
N.A.
N.A.
62.6
58.3
60
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
46.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
0
22
0
0
8
8
0
8
65
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
15
% C
% Asp:
43
0
0
0
86
0
29
15
0
0
0
8
36
0
0
% D
% Glu:
36
0
0
0
0
8
58
0
0
0
0
50
36
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
29
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
8
8
0
0
8
0
0
% H
% Ile:
0
22
8
86
0
0
0
0
0
0
0
0
0
58
0
% I
% Lys:
8
0
8
0
8
0
8
0
0
0
8
0
0
0
0
% K
% Leu:
0
8
0
0
0
8
0
0
8
79
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
29
0
8
0
0
8
0
0
% N
% Pro:
8
8
8
8
0
0
0
0
15
0
58
15
0
0
0
% P
% Gln:
0
0
43
0
0
65
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
8
0
22
0
0
15
8
0
15
22
% S
% Thr:
8
0
8
0
0
0
0
8
0
0
8
0
0
8
0
% T
% Val:
0
58
8
8
0
0
0
0
0
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
43
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _