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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARL2
All Species:
41.52
Human Site:
S45
Identified Species:
65.24
UniProt:
P36404
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36404
NP_001658.2
184
20878
S45
G
E
D
I
D
T
I
S
P
T
L
G
F
N
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118213
180
19952
S41
G
E
D
I
D
T
I
S
P
T
L
G
F
N
I
Dog
Lupus familis
XP_540874
184
20812
S45
G
E
D
I
D
T
I
S
P
T
L
G
F
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0J4
184
20845
S45
G
E
D
V
D
T
I
S
P
T
L
G
F
N
I
Rat
Rattus norvegicus
O08697
184
20817
S45
G
E
D
V
D
T
I
S
P
T
L
G
F
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q8QHI3
182
20390
T46
S
E
D
I
S
H
I
T
P
T
Q
G
F
N
I
Zebra Danio
Brachydanio rerio
Q1MTE5
182
20408
T46
S
E
D
I
T
H
I
T
P
T
Q
G
F
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q06849
184
20816
S45
G
E
P
I
D
T
I
S
P
T
L
G
F
N
I
Honey Bee
Apis mellifera
XP_394559
184
21013
S45
G
E
P
I
D
T
I
S
P
T
L
G
F
N
I
Nematode Worm
Caenorhab. elegans
Q19705
184
20981
E45
D
E
P
T
D
T
I
E
P
T
L
G
F
D
I
Sea Urchin
Strong. purpuratus
XP_787365
196
22463
S57
G
E
D
I
N
T
I
S
P
T
L
G
F
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49076
181
20642
I46
L
G
E
I
V
T
T
I
P
T
I
G
F
N
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZPX1
185
21059
S45
G
E
D
T
S
V
I
S
P
T
L
G
F
N
I
Baker's Yeast
Sacchar. cerevisiae
P38116
183
20416
K47
I
G
E
V
V
T
T
K
P
T
I
G
F
N
V
Red Bread Mold
Neurospora crassa
Q7RVM2
185
20961
I49
L
G
E
V
V
T
T
I
P
T
I
G
F
N
V
Conservation
Percent
Protein Identity:
100
N.A.
89.1
98.9
N.A.
96.1
95.1
N.A.
N.A.
N.A.
52.7
52.1
N.A.
75.5
76.6
62.5
78
Protein Similarity:
100
N.A.
90.2
98.9
N.A.
98.3
98.3
N.A.
N.A.
N.A.
76
75
N.A.
86.9
90.7
79.8
89.2
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
66.6
66.6
N.A.
93.3
93.3
66.6
93.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
73.3
73.3
N.A.
93.3
93.3
73.3
100
Percent
Protein Identity:
N.A.
47.2
N.A.
64.3
45.1
44.8
Protein Similarity:
N.A.
67.9
N.A.
83.2
64.1
66.4
P-Site Identity:
N.A.
46.6
N.A.
80
40
40
P-Site Similarity:
N.A.
66.6
N.A.
80
66.6
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
60
0
54
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
80
20
0
0
0
0
7
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% F
% Gly:
60
20
0
0
0
0
0
0
0
0
0
100
0
0
0
% G
% His:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
60
0
0
80
14
0
0
20
0
0
0
80
% I
% Lys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% K
% Leu:
14
0
0
0
0
0
0
0
0
0
67
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
0
94
0
% N
% Pro:
0
0
20
0
0
0
0
0
100
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
14
0
0
0
14
0
0
60
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
14
7
80
20
14
0
100
0
0
0
0
0
% T
% Val:
0
0
0
27
20
7
0
0
0
0
0
0
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _