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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRT2
All Species:
0.61
Human Site:
S497
Identified Species:
1.9
UniProt:
P35908
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35908
NP_000414.2
639
65433
S497
R
M
S
G
D
L
S
S
N
V
T
V
S
V
T
Chimpanzee
Pan troglodytes
A5A6M6
637
65471
P494
R
M
S
G
E
C
A
P
N
V
G
V
S
V
S
Rhesus Macaque
Macaca mulatta
XP_001098486
641
65483
S499
E
G
E
E
C
R
M
S
G
D
L
S
S
N
V
Dog
Lupus familis
XP_850012
599
65292
N451
R
M
S
G
E
Y
T
N
A
V
S
I
S
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3TTY5
707
70904
D518
R
M
S
G
D
F
S
D
N
V
S
V
S
I
T
Rat
Rattus norvegicus
Q6IG02
685
69109
D517
R
M
S
G
D
F
S
D
N
V
S
V
S
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521385
725
77472
N469
R
M
S
G
E
Y
S
N
S
V
S
I
S
V
I
Chicken
Gallus gallus
O93532
492
53785
R351
I
E
N
A
K
A
Q
R
A
K
M
E
A
A
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.4
95.6
51.6
N.A.
74.2
75.3
N.A.
49.2
47.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
74.6
97
63.8
N.A.
80.4
82
N.A.
61.7
59.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
13.3
46.6
N.A.
73.3
80
N.A.
53.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
13.3
80
N.A.
86.6
86.6
N.A.
86.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
13
13
0
25
0
0
0
13
13
0
% A
% Cys:
0
0
0
0
13
13
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
38
0
0
25
0
13
0
0
0
0
0
% D
% Glu:
13
13
13
13
38
0
0
0
0
0
0
13
0
0
0
% E
% Phe:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
75
0
0
0
0
13
0
13
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
0
0
0
25
0
13
38
% I
% Lys:
0
0
0
0
13
0
0
0
0
13
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
13
0
0
0
0
13
0
0
0
0
% L
% Met:
0
75
0
0
0
0
13
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
25
50
0
0
0
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% Q
% Arg:
75
0
0
0
0
13
0
13
0
0
0
0
0
0
0
% R
% Ser:
0
0
75
0
0
0
50
25
13
0
50
13
88
0
13
% S
% Thr:
0
0
0
0
0
0
13
0
0
0
13
0
0
0
38
% T
% Val:
0
0
0
0
0
0
0
0
0
75
0
50
0
63
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _