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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1A
All Species:
35.45
Human Site:
Y311
Identified Species:
65
UniProt:
P35813
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35813
NP_066283.1
382
42448
Y311
K
E
A
E
L
D
K
Y
L
E
C
R
V
E
E
Chimpanzee
Pan troglodytes
XP_001167412
430
48336
Y359
K
E
A
E
L
D
K
Y
L
E
C
R
V
E
E
Rhesus Macaque
Macaca mulatta
XP_001095896
354
39114
S285
K
G
S
R
D
N
M
S
V
I
L
I
C
F
P
Dog
Lupus familis
XP_537467
382
42427
Y311
K
E
A
E
L
D
K
Y
L
E
S
R
V
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P49443
382
42414
Y311
K
E
A
E
L
D
K
Y
L
E
S
R
V
E
E
Rat
Rattus norvegicus
P20650
382
42398
Y311
K
E
A
E
L
D
K
Y
L
E
N
R
V
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512797
382
42443
Y311
R
E
A
E
L
D
K
Y
L
E
S
R
V
E
E
Chicken
Gallus gallus
XP_421422
382
42461
Y311
R
E
A
E
L
D
K
Y
L
E
S
R
V
E
E
Frog
Xenopus laevis
NP_001080366
383
42664
Y311
R
E
A
E
L
D
K
Y
L
E
G
R
V
E
D
Zebra Danio
Brachydanio rerio
NP_571504
384
42071
Y318
R
E
A
E
L
D
K
Y
L
E
S
R
V
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49596
356
39046
F296
G
Q
S
P
D
T
L
F
T
K
C
A
R
P
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
E294
I
H
E
Q
L
K
S
E
T
K
L
S
T
V
C
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
Q403
E
A
G
I
Q
I
R
Q
R
P
S
S
D
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.8
92.6
99.4
N.A.
98.1
98.9
N.A.
93.4
93.9
90.5
83.5
N.A.
N.A.
N.A.
36.6
N.A.
Protein Similarity:
100
88.8
92.6
99.7
N.A.
98.9
99.2
N.A.
98.1
98.4
96
92.1
N.A.
N.A.
N.A.
51.5
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
86.6
86.6
80
86.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
26.6
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
93.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
27.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
70
0
0
0
0
0
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
24
0
8
0
8
% C
% Asp:
0
0
0
0
16
70
0
0
0
0
0
0
8
0
16
% D
% Glu:
8
70
8
70
0
0
0
8
0
70
0
0
0
70
62
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
8
8
8
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
8
0
0
0
8
0
8
0
0
0
% I
% Lys:
47
0
0
0
0
8
70
0
0
16
0
0
0
0
0
% K
% Leu:
0
0
0
0
77
0
8
0
70
0
16
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
8
% P
% Gln:
0
8
0
8
8
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
31
0
0
8
0
0
8
0
8
0
0
70
8
0
0
% R
% Ser:
0
0
16
0
0
0
8
8
0
0
47
16
0
8
0
% S
% Thr:
0
0
0
0
0
8
0
0
16
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
0
70
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _