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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1A
All Species:
32.12
Human Site:
Y24
Identified Species:
58.89
UniProt:
P35813
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35813
NP_066283.1
382
42448
Y24
G
Q
G
N
G
L
R
Y
G
L
S
S
M
Q
G
Chimpanzee
Pan troglodytes
XP_001167412
430
48336
Y72
G
Q
G
N
G
L
R
Y
G
L
S
S
M
Q
G
Rhesus Macaque
Macaca mulatta
XP_001095896
354
39114
K12
L
D
K
P
K
M
E
K
H
N
A
Q
G
Q
G
Dog
Lupus familis
XP_537467
382
42427
Y24
G
Q
G
N
G
L
R
Y
G
L
S
S
M
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
P49443
382
42414
Y24
G
Q
G
N
G
L
R
Y
G
L
S
S
M
Q
G
Rat
Rattus norvegicus
P20650
382
42398
Y24
G
Q
G
N
G
L
R
Y
G
L
S
S
M
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512797
382
42443
Y24
G
Q
G
N
G
L
R
Y
G
L
S
S
M
Q
G
Chicken
Gallus gallus
XP_421422
382
42461
Y24
G
Q
G
N
G
L
R
Y
G
L
S
S
M
Q
G
Frog
Xenopus laevis
NP_001080366
383
42664
Y24
G
Q
G
N
E
L
R
Y
G
L
S
S
M
Q
G
Zebra Danio
Brachydanio rerio
NP_571504
384
42071
G31
Y
G
L
S
S
M
Q
G
W
R
V
E
M
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49596
356
39046
S14
E
P
V
T
K
K
E
S
A
S
C
A
N
E
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
K21
S
E
D
G
E
N
D
K
L
R
F
G
L
S
S
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
D19
K
E
H
H
S
G
T
D
C
L
T
A
F
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.8
92.6
99.4
N.A.
98.1
98.9
N.A.
93.4
93.9
90.5
83.5
N.A.
N.A.
N.A.
36.6
N.A.
Protein Similarity:
100
88.8
92.6
99.7
N.A.
98.9
99.2
N.A.
98.1
98.4
96
92.1
N.A.
N.A.
N.A.
51.5
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
100
100
93.3
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
100
100
93.3
33.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
27.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
8
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
8
8
0
0
0
0
0
0
8
% D
% Glu:
8
16
0
0
16
0
16
0
0
0
0
8
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
62
8
62
8
54
8
0
8
62
0
0
8
8
8
70
% G
% His:
0
0
8
8
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
0
16
8
0
16
0
0
0
0
0
0
0
% K
% Leu:
8
0
8
0
0
62
0
0
8
70
0
0
8
0
8
% L
% Met:
0
0
0
0
0
16
0
0
0
0
0
0
70
0
0
% M
% Asn:
0
0
0
62
0
8
0
0
0
8
0
0
8
0
8
% N
% Pro:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
62
0
0
0
0
8
0
0
0
0
8
0
70
0
% Q
% Arg:
0
0
0
0
0
0
62
0
0
16
0
0
0
0
0
% R
% Ser:
8
0
0
8
16
0
0
8
0
8
62
62
0
8
8
% S
% Thr:
0
0
0
8
0
0
8
0
0
0
8
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _