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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1A
All Species:
39.7
Human Site:
T274
Identified Species:
72.78
UniProt:
P35813
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35813
NP_066283.1
382
42448
T274
V
C
N
E
V
V
D
T
C
L
Y
K
G
S
R
Chimpanzee
Pan troglodytes
XP_001167412
430
48336
T322
V
C
N
E
V
V
D
T
C
L
Y
K
G
S
R
Rhesus Macaque
Macaca mulatta
XP_001095896
354
39114
E248
I
W
D
V
M
G
N
E
E
L
C
D
F
V
R
Dog
Lupus familis
XP_537467
382
42427
T274
V
C
N
E
V
V
D
T
C
L
Y
K
G
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P49443
382
42414
T274
V
C
N
E
V
V
D
T
C
L
Y
K
G
S
R
Rat
Rattus norvegicus
P20650
382
42398
T274
V
C
N
E
V
V
D
T
C
L
Y
K
G
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512797
382
42443
T274
V
C
N
E
I
V
D
T
C
L
Y
K
G
S
R
Chicken
Gallus gallus
XP_421422
382
42461
T274
V
C
N
E
I
V
D
T
C
L
Y
K
G
S
R
Frog
Xenopus laevis
NP_001080366
383
42664
T274
V
C
N
E
I
V
D
T
C
L
Y
K
G
S
R
Zebra Danio
Brachydanio rerio
NP_571504
384
42071
T281
V
C
N
E
I
V
D
T
C
L
Y
K
G
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49596
356
39046
E259
D
P
Q
S
I
C
E
E
L
L
T
R
C
L
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81716
355
39336
T257
T
A
D
P
D
I
N
T
I
D
L
C
D
D
D
Baker's Yeast
Sacchar. cerevisiae
P34221
468
51372
T366
M
E
I
D
D
L
D
T
E
L
D
S
S
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.8
92.6
99.4
N.A.
98.1
98.9
N.A.
93.4
93.9
90.5
83.5
N.A.
N.A.
N.A.
36.6
N.A.
Protein Similarity:
100
88.8
92.6
99.7
N.A.
98.9
99.2
N.A.
98.1
98.4
96
92.1
N.A.
N.A.
N.A.
51.5
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
93.3
93.3
93.3
93.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
27.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
44.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
8
% A
% Cys:
0
70
0
0
0
8
0
0
70
0
8
8
8
0
0
% C
% Asp:
8
0
16
8
16
0
77
0
0
8
8
8
8
8
8
% D
% Glu:
0
8
0
70
0
0
8
16
16
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
70
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
39
8
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
8
93
8
0
0
8
0
% L
% Met:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
70
0
0
0
16
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
77
% R
% Ser:
0
0
0
8
0
0
0
0
0
0
0
8
8
70
0
% S
% Thr:
8
0
0
0
0
0
0
85
0
0
8
0
0
0
8
% T
% Val:
70
0
0
8
39
70
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
70
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _