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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEK
All Species:
24.55
Human Site:
S288
Identified Species:
49.09
UniProt:
P35659
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35659
NP_001128181.1
375
42674
S288
N
V
K
K
A
D
S
S
T
T
K
K
N
Q
N
Chimpanzee
Pan troglodytes
XP_518259
308
35142
T222
V
K
K
A
D
S
S
T
T
K
K
N
Q
N
S
Rhesus Macaque
Macaca mulatta
XP_001101463
375
42582
S288
N
V
K
K
A
D
S
S
T
T
K
K
N
Q
N
Dog
Lupus familis
XP_853159
361
41239
T275
V
K
K
A
D
S
S
T
T
K
K
N
Q
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNV0
380
43140
S293
N
V
K
K
A
D
S
S
T
T
K
K
N
Q
K
Rat
Rattus norvegicus
Q6AXS3
378
42874
S291
N
V
K
K
A
D
S
S
T
T
K
K
N
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012578
369
42145
S282
N
V
K
K
A
D
S
S
T
T
K
K
N
Q
N
Frog
Xenopus laevis
NP_001167471
391
44331
Q304
S
T
P
N
K
K
N
Q
G
N
A
K
K
E
K
Zebra Danio
Brachydanio rerio
NP_001038741
442
49931
S355
K
T
K
K
A
D
S
S
S
N
R
K
K
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995861
612
65912
D515
S
R
K
R
K
D
S
D
S
E
D
E
E
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181560
201
22965
L115
L
K
P
L
H
K
F
L
F
G
K
M
V
R
D
Poplar Tree
Populus trichocarpa
XP_002318149
574
63311
Q455
D
K
V
N
A
K
K
Q
S
T
K
S
P
S
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
98.9
89.8
N.A.
91.3
92
N.A.
N.A.
81.5
62.6
41.1
N.A.
24.1
N.A.
N.A.
22.6
Protein Similarity:
100
82.1
99.4
93
N.A.
95
96.5
N.A.
N.A.
90.1
77.4
56.5
N.A.
37.7
N.A.
N.A.
35.2
P-Site Identity:
100
26.6
100
26.6
N.A.
93.3
100
N.A.
N.A.
100
6.6
46.6
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
40
100
40
N.A.
93.3
100
N.A.
N.A.
100
26.6
66.6
N.A.
53.3
N.A.
N.A.
20
Percent
Protein Identity:
28.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
59
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
17
59
0
9
0
0
9
0
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
9
9
9
0
% E
% Phe:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
34
75
50
17
25
9
0
0
17
75
59
17
9
25
% K
% Leu:
9
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
42
0
0
17
0
0
9
0
0
17
0
17
42
17
34
% N
% Pro:
0
0
17
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
17
0
0
0
0
17
42
0
% Q
% Arg:
0
9
0
9
0
0
0
0
0
0
9
0
0
9
0
% R
% Ser:
17
0
0
0
0
17
75
50
25
0
0
9
0
9
25
% S
% Thr:
0
17
0
0
0
0
0
17
59
50
0
0
0
0
9
% T
% Val:
17
42
9
0
0
0
0
0
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _