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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DEK All Species: 19.7
Human Site: S276 Identified Species: 39.39
UniProt: P35659 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35659 NP_001128181.1 375 42674 S276 A T S K S K K S V K S A N V K
Chimpanzee Pan troglodytes XP_518259 308 35142 V210 T S K S K K S V K S A N V K K
Rhesus Macaque Macaca mulatta XP_001101463 375 42582 S276 A T S K S K K S V K S A N V K
Dog Lupus familis XP_853159 361 41239 V263 T S K S K K T V K S A N V K K
Cat Felis silvestris
Mouse Mus musculus Q7TNV0 380 43140 S281 A T A K S K K S V K S A N V K
Rat Rattus norvegicus Q6AXS3 378 42874 S279 A T T K S K K S V K S A N V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012578 369 42145 T270 V T S K P K K T V K G A N V K
Frog Xenopus laevis NP_001167471 391 44331 K292 A A K S A N V K K A D S S T P
Zebra Danio Brachydanio rerio NP_001038741 442 49931 A343 A A K R K A P A K P V P K T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_995861 612 65912 G503 S A G R R G R G R G A A S R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181560 201 22965 T103 V A H F L E K T K S Q D L K P
Poplar Tree Populus trichocarpa XP_002318149 574 63311 S443 K E S P K D R S A S S K D K V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.1 98.9 89.8 N.A. 91.3 92 N.A. N.A. 81.5 62.6 41.1 N.A. 24.1 N.A. N.A. 22.6
Protein Similarity: 100 82.1 99.4 93 N.A. 95 96.5 N.A. N.A. 90.1 77.4 56.5 N.A. 37.7 N.A. N.A. 35.2
P-Site Identity: 100 13.3 100 13.3 N.A. 93.3 93.3 N.A. N.A. 73.3 6.6 13.3 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 26.6 100 26.6 N.A. 100 100 N.A. N.A. 80 26.6 26.6 N.A. 46.6 N.A. N.A. 20
Percent
Protein Identity: 28.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 41.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 34 9 0 9 9 0 9 9 9 25 50 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 0 0 9 9 9 0 0 % D
% Glu: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 9 0 9 0 9 9 0 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 34 42 34 59 50 9 42 42 0 9 9 34 75 % K
% Leu: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 17 42 0 0 % N
% Pro: 0 0 0 9 9 0 9 0 0 9 0 9 0 0 17 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 17 9 0 17 0 9 0 0 0 0 9 0 % R
% Ser: 9 17 34 25 34 0 9 42 0 34 42 9 17 0 0 % S
% Thr: 17 42 9 0 0 0 9 17 0 0 0 0 0 17 0 % T
% Val: 17 0 0 0 0 0 9 17 42 0 9 0 17 42 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _