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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPB2
All Species:
35.76
Human Site:
S423
Identified Species:
87.41
UniProt:
P35606
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35606
NP_004757.1
906
102487
S423
K
N
F
K
E
K
K
S
F
K
P
D
F
G
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534283
906
102370
S423
K
N
F
K
E
K
K
S
F
K
P
D
F
G
A
Cat
Felis silvestris
Mouse
Mus musculus
O55029
905
102431
S423
K
N
F
K
E
K
K
S
F
K
P
D
F
G
A
Rat
Rattus norvegicus
O35142
905
102533
S423
K
N
F
K
E
K
K
S
F
K
P
D
F
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505405
1064
119826
S572
K
N
F
K
E
K
K
S
F
K
P
D
F
G
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O62621
914
102694
S425
R
N
F
K
E
R
K
S
F
T
P
E
Y
G
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20168
1000
111088
S426
K
N
F
K
D
H
K
S
I
R
S
D
M
V
L
Sea Urchin
Strong. purpuratus
XP_001191382
1012
113829
S499
K
N
F
K
E
K
K
S
F
K
P
D
F
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAA0
920
103951
T423
K
N
F
Q
E
K
K
T
V
R
P
T
F
S
A
Baker's Yeast
Sacchar. cerevisiae
P41811
889
99426
S427
K
N
F
K
E
V
T
S
W
S
V
P
M
H
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99
N.A.
98.2
97.2
N.A.
81.7
N.A.
N.A.
N.A.
N.A.
68.3
N.A.
58
62
Protein Similarity:
100
N.A.
N.A.
99.5
N.A.
99
98.4
N.A.
83.2
N.A.
N.A.
N.A.
N.A.
82.8
N.A.
73.5
74.4
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
46.6
100
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
60
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.8
43.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
75.2
64.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
80
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
70
0
0
0
% D
% Glu:
0
0
0
0
90
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
100
0
0
0
0
0
70
0
0
0
70
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
90
0
0
90
0
70
90
0
0
60
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% M
% Asn:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
80
10
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
10
0
0
0
20
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
90
0
10
10
0
0
10
10
% S
% Thr:
0
0
0
0
0
0
10
10
0
10
0
10
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
10
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _