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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCK1
All Species:
44.24
Human Site:
S230
Identified Species:
97.33
UniProt:
P35558
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35558
NP_002582.3
622
69195
S230
P
D
R
R
E
I
I
S
F
G
S
G
Y
G
G
Chimpanzee
Pan troglodytes
XP_514745
622
69186
S230
P
D
R
R
E
I
I
S
F
G
S
G
Y
G
G
Rhesus Macaque
Macaca mulatta
XP_001086710
622
69152
S230
P
D
R
R
E
I
I
S
F
G
S
G
Y
G
G
Dog
Lupus familis
XP_537379
640
70784
S248
P
D
Q
R
E
I
V
S
F
G
S
G
Y
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2V4
622
69336
S230
P
D
R
R
E
I
I
S
F
G
S
G
Y
G
G
Rat
Rattus norvegicus
P07379
622
69397
S230
P
D
R
R
E
I
I
S
F
G
S
G
Y
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518084
681
75076
S289
P
D
R
R
E
I
V
S
F
G
S
G
Y
G
G
Chicken
Gallus gallus
P05153
622
69510
S230
P
D
R
R
E
I
I
S
F
G
S
G
Y
G
G
Frog
Xenopus laevis
NP_001079946
622
69844
S230
P
E
Q
R
E
I
I
S
F
G
S
G
Y
G
G
Zebra Danio
Brachydanio rerio
NP_999916
630
69674
S231
P
D
Q
R
K
I
V
S
F
G
S
G
Y
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20007
647
71111
S256
P
A
E
N
L
I
V
S
Y
G
S
G
Y
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.4
68.9
N.A.
90.8
90.8
N.A.
66
83.7
80.7
73
N.A.
62.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
99.1
81.8
N.A.
95.8
95.8
N.A.
77.8
92.9
90.3
84.5
N.A.
75.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
93.3
100
86.6
80
N.A.
60
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
82
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
10
0
82
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
91
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
100
0
100
0
100
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
100
64
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
28
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
64
91
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
100
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
37
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
100
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _