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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CBS
All Species:
12.34
Human Site:
T5
Identified Species:
24.68
UniProt:
P35520
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35520
NP_000062.1
551
60587
T5
_
_
_
M
P
S
E
T
P
Q
A
E
V
G
P
Chimpanzee
Pan troglodytes
XP_001142443
593
64952
T5
_
_
_
M
P
S
E
T
P
Q
A
E
V
G
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853796
764
82787
S5
_
_
_
M
A
S
P
S
R
L
P
G
L
H
C
Cat
Felis silvestris
Mouse
Mus musculus
Q91WT9
561
61525
T5
_
_
_
M
P
S
G
T
S
Q
C
E
D
G
S
Rat
Rattus norvegicus
P32232
561
61436
T5
_
_
_
M
P
S
G
T
S
Q
C
E
D
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511742
606
66744
L5
_
_
_
M
P
S
E
L
S
K
A
E
E
K
P
Chicken
Gallus gallus
XP_416752
558
61762
V12
M
S
E
K
P
V
P
V
S
K
A
K
P
D
T
Frog
Xenopus laevis
NP_001086820
562
62067
D9
P
A
V
P
P
T
T
D
S
A
A
C
P
H
I
Zebra Danio
Brachydanio rerio
NP_001014367
597
65855
S7
_
M
P
A
V
P
S
S
S
E
S
V
G
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795930
531
58161
Q6
_
_
M
A
T
T
P
Q
N
G
G
V
D
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P80608
325
34188
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32582
507
56003
E5
_
_
_
M
T
K
S
E
Q
Q
A
D
S
R
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
N.A.
52.4
N.A.
82.5
82.3
N.A.
70.7
77.2
74.3
70.3
N.A.
N.A.
N.A.
N.A.
57.7
Protein Similarity:
100
92.5
N.A.
57.7
N.A.
88
88.9
N.A.
79.8
87.2
85.4
79.7
N.A.
N.A.
N.A.
N.A.
74.2
P-Site Identity:
100
100
N.A.
16.6
N.A.
58.3
58.3
N.A.
58.3
13.3
13.3
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
33.3
N.A.
58.3
58.3
N.A.
66.6
26.6
20
21.4
N.A.
N.A.
N.A.
N.A.
7.6
Percent
Protein Identity:
N.A.
27.4
N.A.
N.A.
39.2
N.A.
Protein Similarity:
N.A.
38.4
N.A.
N.A.
55.9
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
25
N.A.
P-Site Similarity:
N.A.
0
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
17
9
0
0
0
0
9
50
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
17
9
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
9
25
9
0
% D
% Glu:
0
0
9
0
0
0
25
9
0
9
0
42
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
17
0
0
9
9
9
9
34
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
17
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
9
0
9
0
0
0
17
0
9
0
17
0
% K
% Leu:
0
0
0
0
0
0
0
9
0
9
0
0
9
0
0
% L
% Met:
9
9
9
59
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
9
0
9
9
59
9
25
0
17
0
9
0
17
0
25
% P
% Gln:
0
0
0
0
0
0
0
9
9
42
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% R
% Ser:
0
9
0
0
0
50
17
17
50
0
9
0
9
0
17
% S
% Thr:
0
0
0
0
17
17
9
34
0
0
0
0
0
9
9
% T
% Val:
0
0
9
0
9
9
0
9
0
0
0
17
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
75
67
59
0
0
0
0
0
0
0
0
0
0
0
0
% _