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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CBS
All Species:
6.36
Human Site:
T333
Identified Species:
12.73
UniProt:
P35520
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35520
NP_000062.1
551
60587
T333
S
N
D
E
E
A
F
T
F
A
R
M
L
I
A
Chimpanzee
Pan troglodytes
XP_001142443
593
64952
T333
S
N
D
E
E
A
F
T
F
A
R
M
L
I
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853796
764
82787
A316
S
N
D
E
E
A
F
A
F
A
R
M
L
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91WT9
561
61525
A330
S
N
D
E
D
S
F
A
F
A
R
M
L
I
A
Rat
Rattus norvegicus
P32232
561
61436
A330
S
N
D
D
D
S
F
A
F
A
R
M
L
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511742
606
66744
A333
C
N
D
E
E
S
F
A
F
A
R
M
L
I
S
Chicken
Gallus gallus
XP_416752
558
61762
A339
S
N
D
E
E
S
F
A
L
A
R
M
L
I
R
Frog
Xenopus laevis
NP_001086820
562
62067
F326
S
N
D
E
E
S
F
F
M
A
R
A
L
I
R
Zebra Danio
Brachydanio rerio
NP_001014367
597
65855
A368
S
N
D
E
E
S
F
A
M
S
R
M
L
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795930
531
58161
V307
V
G
D
K
E
S
F
V
M
S
R
R
L
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P80608
325
34188
P143
E
E
I
Q
A
K
T
P
N
S
Y
I
L
Q
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32582
507
56003
T308
C
E
D
H
P
E
L
T
E
D
D
V
I
V
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
N.A.
52.4
N.A.
82.5
82.3
N.A.
70.7
77.2
74.3
70.3
N.A.
N.A.
N.A.
N.A.
57.7
Protein Similarity:
100
92.5
N.A.
57.7
N.A.
88
88.9
N.A.
79.8
87.2
85.4
79.7
N.A.
N.A.
N.A.
N.A.
74.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
80
66.6
N.A.
73.3
73.3
66.6
66.6
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
86.6
80
73.3
80
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
27.4
N.A.
N.A.
39.2
N.A.
Protein Similarity:
N.A.
38.4
N.A.
N.A.
55.9
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
25
0
50
0
67
0
9
0
0
42
% A
% Cys:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
92
9
17
0
0
0
0
9
9
0
0
0
0
% D
% Glu:
9
17
0
67
67
9
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
84
9
50
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
9
9
84
0
% I
% Lys:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
0
0
0
0
0
9
0
9
0
0
0
92
0
0
% L
% Met:
0
0
0
0
0
0
0
0
25
0
0
67
0
0
0
% M
% Asn:
0
75
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
84
9
0
0
25
% R
% Ser:
67
0
0
0
0
59
0
0
0
25
0
0
0
0
17
% S
% Thr:
0
0
0
0
0
0
9
25
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
9
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _