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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CBS
All Species:
33.94
Human Site:
T262
Identified Species:
67.88
UniProt:
P35520
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35520
NP_000062.1
551
60587
T262
V
G
T
G
G
T
I
T
G
I
A
R
K
L
K
Chimpanzee
Pan troglodytes
XP_001142443
593
64952
T262
V
G
T
G
G
T
I
T
G
I
A
R
K
L
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853796
764
82787
T245
A
G
T
G
G
T
I
T
G
I
A
R
K
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91WT9
561
61525
T259
A
G
T
G
G
T
I
T
G
I
A
R
K
L
K
Rat
Rattus norvegicus
P32232
561
61436
T259
A
G
T
G
G
T
I
T
G
I
A
R
K
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511742
606
66744
T262
A
G
T
G
G
T
I
T
G
I
G
R
K
L
K
Chicken
Gallus gallus
XP_416752
558
61762
T268
A
G
T
G
G
T
I
T
G
I
S
R
K
L
K
Frog
Xenopus laevis
NP_001086820
562
62067
T255
A
G
T
G
G
T
I
T
G
L
A
R
K
L
K
Zebra Danio
Brachydanio rerio
NP_001014367
597
65855
T297
A
G
T
G
G
T
I
T
G
I
A
R
K
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795930
531
58161
K243
T
G
I
G
R
K
L
K
E
L
N
P
H
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P80608
325
34188
N80
L
I
E
P
T
S
G
N
T
G
I
G
L
A
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32582
507
56003
E244
D
I
T
D
Y
K
V
E
G
I
G
Y
D
F
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
N.A.
52.4
N.A.
82.5
82.3
N.A.
70.7
77.2
74.3
70.3
N.A.
N.A.
N.A.
N.A.
57.7
Protein Similarity:
100
92.5
N.A.
57.7
N.A.
88
88.9
N.A.
79.8
87.2
85.4
79.7
N.A.
N.A.
N.A.
N.A.
74.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
86.6
86.6
86.6
93.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
86.6
93.3
93.3
93.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
27.4
N.A.
N.A.
39.2
N.A.
Protein Similarity:
N.A.
38.4
N.A.
N.A.
55.9
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
0
0
0
0
0
0
0
0
59
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
9
0
0
0
0
9
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% F
% Gly:
0
84
0
84
75
0
9
0
84
9
17
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
17
9
0
0
0
75
0
0
75
9
0
0
9
0
% I
% Lys:
0
0
0
0
0
17
0
9
0
0
0
0
75
0
84
% K
% Leu:
9
0
0
0
0
0
9
0
0
17
0
0
9
75
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
75
0
0
0
% R
% Ser:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% S
% Thr:
9
0
84
0
9
75
0
75
9
0
0
0
0
0
0
% T
% Val:
17
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _