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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CBS
All Species:
31.82
Human Site:
S147
Identified Species:
63.64
UniProt:
P35520
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35520
NP_000062.1
551
60587
S147
D
T
I
I
E
P
T
S
G
N
T
G
I
G
L
Chimpanzee
Pan troglodytes
XP_001142443
593
64952
S147
D
T
I
I
E
P
T
S
G
N
T
G
I
G
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853796
764
82787
G129
T
I
I
E
P
T
S
G
N
T
G
I
G
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91WT9
561
61525
S144
D
T
I
I
E
P
T
S
G
N
T
G
I
G
L
Rat
Rattus norvegicus
P32232
561
61436
S144
D
T
I
I
E
P
T
S
G
N
T
G
I
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511742
606
66744
S147
D
T
I
I
E
P
T
S
G
N
T
G
I
G
L
Chicken
Gallus gallus
XP_416752
558
61762
S153
D
T
I
I
E
P
T
S
G
N
T
G
I
G
L
Frog
Xenopus laevis
NP_001086820
562
62067
S140
D
T
I
I
E
P
T
S
G
N
T
G
I
G
L
Zebra Danio
Brachydanio rerio
NP_001014367
597
65855
S182
D
T
I
I
E
P
T
S
G
N
T
G
I
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795930
531
58161
L130
N
T
G
I
G
L
A
L
V
A
A
V
K
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P80608
325
34188
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32582
507
56003
D133
T
P
T
A
A
A
W
D
S
P
E
S
H
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
N.A.
52.4
N.A.
82.5
82.3
N.A.
70.7
77.2
74.3
70.3
N.A.
N.A.
N.A.
N.A.
57.7
Protein Similarity:
100
92.5
N.A.
57.7
N.A.
88
88.9
N.A.
79.8
87.2
85.4
79.7
N.A.
N.A.
N.A.
N.A.
74.2
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
N.A.
13.3
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
27.4
N.A.
N.A.
39.2
N.A.
Protein Similarity:
N.A.
38.4
N.A.
N.A.
55.9
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
0
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
9
9
0
0
9
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
67
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
9
0
0
9
67
0
9
67
9
75
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
9
75
75
0
0
0
0
0
0
0
9
67
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
0
0
0
9
0
9
0
0
0
0
0
9
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
9
67
0
0
0
0
0
% N
% Pro:
0
9
0
0
9
67
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
9
67
9
0
0
9
0
0
0
% S
% Thr:
17
75
9
0
0
9
67
0
0
9
67
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _