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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCN4A
All Species:
18.18
Human Site:
T457
Identified Species:
50
UniProt:
P35499
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35499
NP_000325.4
1836
208061
T457
Y
A
E
Q
N
E
A
T
L
A
E
D
K
E
K
Chimpanzee
Pan troglodytes
XP_001152236
1796
203555
L449
E
A
E
F
Q
Q
M
L
E
Q
L
K
K
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001116451
1837
208223
T458
Y
A
E
Q
N
E
A
T
L
A
E
D
K
E
K
Dog
Lupus familis
XP_853396
1837
207954
T451
Y
A
E
Q
N
E
A
T
L
A
E
D
Q
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER60
1841
208779
T451
Y
A
E
Q
N
E
A
T
L
A
E
D
Q
E
K
Rat
Rattus norvegicus
P15390
1840
208848
T451
Y
A
E
Q
N
E
A
T
L
A
E
D
Q
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
L438
K
E
E
E
F
Q
R
L
L
E
Q
L
K
N
Q
Tiger Blowfish
Takifugu rubipres
Q2XVR7
1892
213080
L450
K
E
E
E
F
Q
R
L
L
E
Q
L
K
N
Q
Fruit Fly
Dros. melanogaster
P35500
2131
239344
K575
R
G
S
R
S
S
H
K
Y
T
I
R
N
G
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.4
97.5
94.5
N.A.
92.4
92.7
N.A.
N.A.
N.A.
N.A.
70.3
66
42
N.A.
N.A.
N.A.
Protein Similarity:
100
81.7
98.5
96.7
N.A.
95
95
N.A.
N.A.
N.A.
N.A.
81.6
77.4
58.1
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
20
20
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
46.6
46.6
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
67
0
0
0
0
56
0
0
56
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
56
0
0
0
% D
% Glu:
12
23
89
23
0
56
0
0
12
23
56
0
0
56
0
% E
% Phe:
0
0
0
12
23
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
23
0
0
0
0
0
0
12
0
0
0
12
56
0
56
% K
% Leu:
0
0
0
0
0
0
0
34
78
0
12
23
0
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
56
0
0
0
0
0
0
0
12
23
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
56
12
34
0
0
0
12
23
0
34
12
34
% Q
% Arg:
12
0
0
12
0
0
23
0
0
0
0
12
0
0
12
% R
% Ser:
0
0
12
0
12
12
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
56
0
12
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
56
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _