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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOXD12
All Species:
2.12
Human Site:
T166
Identified Species:
3.89
UniProt:
P35452
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35452
NP_067016.3
270
29031
T166
A
P
G
F
K
D
D
T
K
G
P
L
N
L
N
Chimpanzee
Pan troglodytes
A2T7D1
340
38377
C231
G
L
P
E
E
R
S
C
L
A
E
V
S
V
S
Rhesus Macaque
Macaca mulatta
A2D635
342
38100
P199
L
G
G
K
V
S
F
P
E
T
P
K
S
D
N
Dog
Lupus familis
XP_545535
270
28910
A166
A
A
G
F
K
D
D
A
K
G
P
L
N
L
N
Cat
Felis silvestris
Mouse
Mus musculus
P23812
268
29180
G166
S
F
K
E
D
T
K
G
P
L
N
L
N
M
A
Rat
Rattus norvegicus
XP_001063522
268
29219
G166
N
F
K
E
D
T
K
G
P
L
N
L
N
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511494
270
28958
A166
A
A
A
F
R
D
L
A
K
S
P
L
N
L
N
Chicken
Gallus gallus
P24343
266
29995
V166
K
E
D
I
K
N
S
V
N
L
N
L
T
V
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90471
262
29721
A166
K
Q
S
V
S
S
I
A
P
F
Q
P
S
L
S
Tiger Blowfish
Takifugu rubipres
Q1KKT2
261
29132
S171
Q
N
P
I
H
G
S
S
S
Q
T
C
N
R
S
Fruit Fly
Dros. melanogaster
P09087
493
55078
S356
G
Y
P
S
E
N
Y
S
S
S
G
A
S
G
G
Honey Bee
Apis mellifera
XP_394119
570
58624
K192
G
S
S
R
D
N
R
K
A
G
T
L
S
F
W
Nematode Worm
Caenorhab. elegans
NP_499573
275
30519
Q169
W
P
Y
S
Y
P
Q
Q
Y
P
F
A
N
Y
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.3
24.8
91.1
N.A.
85.9
86.3
N.A.
72.5
65.1
N.A.
45.1
45.5
21.2
21.3
27.2
N.A.
Protein Similarity:
100
39.4
37.4
92.5
N.A.
88.1
88.8
N.A.
79.6
77
N.A.
60.3
58.1
31
29.4
41
N.A.
P-Site Identity:
100
0
20
86.6
N.A.
13.3
13.3
N.A.
60
13.3
N.A.
6.6
6.6
0
13.3
13.3
N.A.
P-Site Similarity:
100
33.3
33.3
86.6
N.A.
26.6
20
N.A.
66.6
26.6
N.A.
20
20
26.6
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
16
8
0
0
0
0
24
8
8
0
16
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
0
0
8
0
24
24
16
0
0
0
0
0
0
8
0
% D
% Glu:
0
8
0
24
16
0
0
0
8
0
8
0
0
0
0
% E
% Phe:
0
16
0
24
0
0
8
0
0
8
8
0
0
8
0
% F
% Gly:
24
8
24
0
0
8
0
16
0
24
8
0
0
8
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
16
0
16
8
24
0
16
8
24
0
0
8
0
0
0
% K
% Leu:
8
8
0
0
0
0
8
0
8
24
0
54
0
31
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% M
% Asn:
8
8
0
0
0
24
0
0
8
0
24
0
54
0
31
% N
% Pro:
0
16
24
0
0
8
0
8
24
8
31
8
0
0
0
% P
% Gln:
8
8
0
0
0
0
8
8
0
8
8
0
0
0
8
% Q
% Arg:
0
0
0
8
8
8
8
0
0
0
0
0
0
8
0
% R
% Ser:
8
8
16
16
8
16
24
16
16
16
0
0
39
0
31
% S
% Thr:
0
0
0
0
0
16
0
8
0
8
16
0
8
0
0
% T
% Val:
0
0
0
8
8
0
0
8
0
0
0
8
0
16
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
8
0
8
0
8
0
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _