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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THBS2
All Species:
20
Human Site:
Y626
Identified Species:
44
UniProt:
P35442
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35442
NP_003238.2
1172
129991
Y626
C
L
P
C
P
P
R
Y
R
G
N
Q
P
V
G
Chimpanzee
Pan troglodytes
XP_510294
1457
160594
F911
C
L
P
C
P
P
R
F
T
G
S
Q
P
F
G
Rhesus Macaque
Macaca mulatta
XP_001096616
1200
132829
Y654
C
L
P
C
P
P
R
Y
R
G
S
Q
P
T
G
Dog
Lupus familis
XP_541204
1449
159123
Y903
C
L
P
C
P
P
R
Y
K
G
S
Q
P
F
G
Cat
Felis silvestris
Mouse
Mus musculus
Q03350
1172
129893
Y626
C
L
P
C
P
P
R
Y
K
G
N
Q
P
F
G
Rat
Rattus norvegicus
P35444
755
82645
D308
V
D
R
D
R
I
G
D
A
C
D
P
D
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512789
948
105338
N501
D
N
C
P
H
L
P
N
S
G
Q
E
D
F
D
Chicken
Gallus gallus
P35440
1178
131798
Y632
C
L
P
C
P
P
R
Y
K
G
S
Q
P
Y
G
Frog
Xenopus laevis
P35448
1173
130001
F627
C
L
P
C
P
P
R
F
T
G
T
Q
P
F
G
Zebra Danio
Brachydanio rerio
Q8JHW2
962
105573
K515
D
A
D
G
D
G
I
K
N
V
E
D
N
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783107
1328
146186
Y753
C
Q
E
C
P
T
G
Y
R
G
N
Q
P
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
92.5
72.2
N.A.
88.4
36
N.A.
70
79.5
61.5
36.8
N.A.
N.A.
N.A.
N.A.
44.2
Protein Similarity:
100
62.3
94
75.4
N.A.
93.3
44.4
N.A.
75.6
88.8
75.1
51.2
N.A.
N.A.
N.A.
N.A.
57
P-Site Identity:
100
73.3
86.6
80
N.A.
86.6
0
N.A.
6.6
80
73.3
0
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
86.6
93.3
93.3
N.A.
93.3
6.6
N.A.
13.3
93.3
80
0
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% A
% Cys:
73
0
10
73
0
0
0
0
0
10
0
0
0
10
0
% C
% Asp:
19
10
10
10
10
0
0
10
0
0
10
10
19
0
19
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
19
0
0
0
0
0
46
0
% F
% Gly:
0
0
0
10
0
10
19
0
0
82
0
0
0
0
73
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
28
0
0
0
0
0
0
% K
% Leu:
0
64
0
0
0
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
10
10
0
28
0
10
10
0
% N
% Pro:
0
0
64
10
73
64
10
0
0
0
0
10
73
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
10
73
0
0
0
% Q
% Arg:
0
0
10
0
10
0
64
0
28
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
0
10
0
37
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
19
0
10
0
0
10
0
% T
% Val:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _