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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THBS2
All Species:
22.73
Human Site:
Y1145
Identified Species:
50
UniProt:
P35442
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35442
NP_003238.2
1172
129991
Y1145
G
P
I
Y
D
Q
T
Y
A
G
G
R
L
G
L
Chimpanzee
Pan troglodytes
XP_510294
1457
160594
Y1430
G
P
I
Y
D
K
T
Y
A
G
G
R
L
G
L
Rhesus Macaque
Macaca mulatta
XP_001096616
1200
132829
Y1173
G
P
I
Y
D
Q
T
Y
A
G
G
R
L
G
L
Dog
Lupus familis
XP_541204
1449
159123
Y1422
G
P
I
Y
D
Q
T
Y
A
G
G
R
L
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q03350
1172
129893
Y1145
G
P
I
Y
D
Q
T
Y
A
G
G
R
L
G
L
Rat
Rattus norvegicus
P35444
755
82645
N729
V
F
C
F
S
Q
E
N
I
I
W
A
N
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512789
948
105338
A922
P
I
Y
D
Q
T
Y
A
G
G
R
L
G
L
F
Chicken
Gallus gallus
P35440
1178
131798
F1151
G
P
I
Y
D
T
T
F
A
G
G
R
L
G
L
Frog
Xenopus laevis
P35448
1173
130001
Y1146
G
P
I
Y
D
K
T
Y
A
G
G
R
L
G
L
Zebra Danio
Brachydanio rerio
Q8JHW2
962
105573
N936
Q
E
N
I
I
W
S
N
L
R
Y
R
C
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783107
1328
146186
L1273
G
P
L
Y
D
S
T
L
R
G
G
R
L
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
92.5
72.2
N.A.
88.4
36
N.A.
70
79.5
61.5
36.8
N.A.
N.A.
N.A.
N.A.
44.2
Protein Similarity:
100
62.3
94
75.4
N.A.
93.3
44.4
N.A.
75.6
88.8
75.1
51.2
N.A.
N.A.
N.A.
N.A.
57
P-Site Identity:
100
93.3
100
100
N.A.
100
6.6
N.A.
6.6
86.6
93.3
6.6
N.A.
N.A.
N.A.
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
6.6
93.3
100
13.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
64
0
0
10
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
10
73
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
10
0
0
0
10
0
0
0
0
0
0
10
% F
% Gly:
73
0
0
0
0
0
0
0
10
82
73
0
10
73
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
64
10
10
0
0
0
10
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
0
10
10
0
0
10
73
19
73
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
19
0
0
0
0
10
10
0
% N
% Pro:
10
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
10
46
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
10
10
82
0
0
10
% R
% Ser:
0
0
0
0
10
10
10
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
19
73
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
10
73
0
0
10
55
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _