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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THBS2
All Species:
5.76
Human Site:
T127
Identified Species:
12.67
UniProt:
P35442
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35442
NP_003238.2
1172
129991
T127
P
A
D
T
L
D
L
T
Y
W
I
D
G
T
R
Chimpanzee
Pan troglodytes
XP_510294
1457
160594
T174
E
R
R
R
A
R
R
T
N
L
P
A
P
P
T
Rhesus Macaque
Macaca mulatta
XP_001096616
1200
132829
I127
P
A
D
T
L
D
L
I
Y
W
I
D
G
T
R
Dog
Lupus familis
XP_541204
1449
159123
T405
P
A
D
T
L
D
L
T
Y
W
I
D
G
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q03350
1172
129893
N127
P
G
D
T
L
D
L
N
Y
W
V
E
G
N
Q
Rat
Rattus norvegicus
P35444
755
82645
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512789
948
105338
N11
S
D
S
A
A
E
V
N
T
I
N
E
S
T
E
Chicken
Gallus gallus
P35440
1178
131798
I133
R
A
N
T
L
D
L
I
Y
W
V
D
G
F
Q
Frog
Xenopus laevis
P35448
1173
130001
S124
G
H
I
F
S
L
I
S
N
G
R
A
R
T
L
Zebra Danio
Brachydanio rerio
Q8JHW2
962
105573
K25
V
W
S
A
Q
S
D
K
K
Q
D
V
P
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783107
1328
146186
P138
K
S
D
S
V
L
M
P
Y
S
Y
R
R
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
92.5
72.2
N.A.
88.4
36
N.A.
70
79.5
61.5
36.8
N.A.
N.A.
N.A.
N.A.
44.2
Protein Similarity:
100
62.3
94
75.4
N.A.
93.3
44.4
N.A.
75.6
88.8
75.1
51.2
N.A.
N.A.
N.A.
N.A.
57
P-Site Identity:
100
6.6
93.3
93.3
N.A.
60
0
N.A.
6.6
60
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
6.6
93.3
100
N.A.
80
0
N.A.
26.6
80
20
0
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
0
19
19
0
0
0
0
0
0
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
46
0
0
46
10
0
0
0
10
37
0
10
0
% D
% Glu:
10
0
0
0
0
10
0
0
0
0
0
19
0
0
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
10
0
0
46
0
10
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
19
0
10
28
0
0
0
10
% I
% Lys:
10
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
46
19
46
0
0
10
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
19
19
0
10
0
0
10
0
% N
% Pro:
37
0
0
0
0
0
0
10
0
0
10
0
19
10
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
28
% Q
% Arg:
10
10
10
10
0
10
10
0
0
0
10
10
19
0
19
% R
% Ser:
10
10
19
10
10
10
0
10
0
10
0
0
10
0
0
% S
% Thr:
0
0
0
46
0
0
0
28
10
0
0
0
0
46
10
% T
% Val:
10
0
0
0
10
0
10
0
0
0
19
10
0
10
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
46
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
55
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _