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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THBS2
All Species:
17.27
Human Site:
S188
Identified Species:
38
UniProt:
P35442
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35442
NP_003238.2
1172
129991
S188
E
H
L
Q
A
E
K
S
R
M
Y
V
A
K
G
Chimpanzee
Pan troglodytes
XP_510294
1457
160594
P235
Q
P
L
R
P
S
W
P
A
S
S
G
L
L
P
Rhesus Macaque
Macaca mulatta
XP_001096616
1200
132829
S188
E
H
L
Q
A
E
K
S
R
M
Y
V
A
K
G
Dog
Lupus familis
XP_541204
1449
159123
T466
E
Q
L
R
T
E
K
T
R
M
Y
V
A
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q03350
1172
129893
S188
E
Q
L
E
V
D
R
S
R
M
Y
V
A
K
G
Rat
Rattus norvegicus
P35444
755
82645
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512789
948
105338
K72
N
L
G
E
N
L
Q
K
V
S
E
D
N
R
I
Chicken
Gallus gallus
P35440
1178
131798
S194
E
Q
L
K
A
E
N
S
R
M
Y
V
A
K
G
Frog
Xenopus laevis
P35448
1173
130001
P185
E
N
A
E
L
D
V
P
I
Q
K
I
F
T
E
Zebra Danio
Brachydanio rerio
Q8JHW2
962
105573
K86
L
Y
N
K
Q
D
N
K
K
Y
L
E
V
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783107
1328
146186
Y199
I
M
Y
G
S
F
V
Y
D
V
T
P
D
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
92.5
72.2
N.A.
88.4
36
N.A.
70
79.5
61.5
36.8
N.A.
N.A.
N.A.
N.A.
44.2
Protein Similarity:
100
62.3
94
75.4
N.A.
93.3
44.4
N.A.
75.6
88.8
75.1
51.2
N.A.
N.A.
N.A.
N.A.
57
P-Site Identity:
100
6.6
100
73.3
N.A.
66.6
0
N.A.
0
80
6.6
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
100
86.6
N.A.
86.6
0
N.A.
20
86.6
33.3
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
28
0
0
0
10
0
0
0
46
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
28
0
0
10
0
0
10
10
0
0
% D
% Glu:
55
0
0
28
0
37
0
0
0
0
10
10
0
0
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
10
10
0
0
0
0
0
0
0
10
0
0
46
% G
% His:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
10
0
0
19
% I
% Lys:
0
0
0
19
0
0
28
19
10
0
10
0
0
46
0
% K
% Leu:
10
10
55
0
10
10
0
0
0
0
10
0
10
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
46
0
0
0
0
0
% M
% Asn:
10
10
10
0
10
0
19
0
0
0
0
0
10
0
0
% N
% Pro:
0
10
0
0
10
0
0
19
0
0
0
10
0
0
10
% P
% Gln:
10
28
0
19
10
0
10
0
0
10
0
0
0
10
0
% Q
% Arg:
0
0
0
19
0
0
10
0
46
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
10
10
0
37
0
19
10
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
10
0
0
10
0
0
10
0
% T
% Val:
0
0
0
0
10
0
19
0
10
10
0
46
10
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
0
10
0
10
46
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _