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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THBS2
All Species:
17.88
Human Site:
S147
Identified Species:
39.33
UniProt:
P35442
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35442
NP_003238.2
1172
129991
S147
E
D
V
G
L
A
D
S
Q
W
K
N
V
T
V
Chimpanzee
Pan troglodytes
XP_510294
1457
160594
A194
S
G
P
G
V
G
P
A
Q
D
R
R
S
G
D
Rhesus Macaque
Macaca mulatta
XP_001096616
1200
132829
S147
E
D
V
G
L
A
D
S
Q
W
K
N
V
T
V
Dog
Lupus familis
XP_541204
1449
159123
S425
E
D
V
G
L
A
D
S
Q
W
K
N
V
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q03350
1172
129893
S147
E
D
V
G
L
A
D
S
Q
W
K
N
V
T
V
Rat
Rattus norvegicus
P35444
755
82645
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512789
948
105338
V31
P
E
V
I
T
E
F
V
G
Q
K
P
E
K
K
Chicken
Gallus gallus
P35440
1178
131798
S153
E
D
V
D
L
A
D
S
Q
W
K
N
L
T
V
Frog
Xenopus laevis
P35448
1173
130001
V144
G
E
R
K
Q
Q
V
V
S
V
E
D
A
V
L
Zebra Danio
Brachydanio rerio
Q8JHW2
962
105573
A45
E
D
V
K
Q
T
V
A
A
V
E
K
L
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783107
1328
146186
N158
S
L
E
F
S
G
L
N
L
E
D
T
E
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
92.5
72.2
N.A.
88.4
36
N.A.
70
79.5
61.5
36.8
N.A.
N.A.
N.A.
N.A.
44.2
Protein Similarity:
100
62.3
94
75.4
N.A.
93.3
44.4
N.A.
75.6
88.8
75.1
51.2
N.A.
N.A.
N.A.
N.A.
57
P-Site Identity:
100
13.3
100
100
N.A.
100
0
N.A.
13.3
86.6
0
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
33.3
100
100
N.A.
100
0
N.A.
20
93.3
26.6
53.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
46
0
19
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
55
0
10
0
0
46
0
0
10
10
10
0
10
10
% D
% Glu:
55
19
10
0
0
10
0
0
0
10
19
0
19
0
0
% E
% Phe:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
46
0
19
0
0
10
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
19
0
0
0
0
0
0
55
10
0
10
10
% K
% Leu:
0
10
0
0
46
0
10
0
10
0
0
0
19
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
46
0
0
0
% N
% Pro:
10
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
19
10
0
0
55
10
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
10
10
0
0
10
% R
% Ser:
19
0
0
0
10
0
0
46
10
0
0
0
10
10
0
% S
% Thr:
0
0
0
0
10
10
0
0
0
0
0
10
0
46
0
% T
% Val:
0
0
64
0
10
0
19
19
0
19
0
0
37
10
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
46
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _