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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
1.21
Human Site:
Y301
Identified Species:
2.05
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
Y301
D
R
E
V
D
K
L
Y
C
F
P
L
D
I
V
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
H301
D
R
E
V
D
K
L
H
C
F
P
L
D
I
V
Rhesus Macaque
Macaca mulatta
P56490
532
60122
P319
E
D
K
P
A
T
D
P
V
L
Q
V
V
Y
K
Dog
Lupus familis
XP_541769
536
61594
Q350
D
R
E
V
D
K
L
Q
C
F
P
L
N
I
V
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
P300
E
R
E
T
V
T
R
P
C
F
R
L
D
V
M
Rat
Rattus norvegicus
P31390
486
55674
F300
E
R
E
T
R
P
C
F
R
L
D
I
M
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
H304
D
G
E
G
V
T
Q
H
C
F
P
I
T
I
V
Chicken
Gallus gallus
P30372
466
51547
S293
S
N
D
S
T
S
V
S
V
V
P
S
N
T
K
Frog
Xenopus laevis
P30544
484
54107
K308
L
S
H
N
P
P
E
K
Q
P
L
S
E
A
S
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
M334
I
F
N
L
S
K
R
M
R
K
S
V
P
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
D342
D
C
H
V
I
V
N
D
K
S
T
E
F
M
L
Honey Bee
Apis mellifera
XP_395477
546
60788
P356
K
S
E
R
S
S
S
P
A
F
D
S
D
E
E
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
E313
K
S
L
N
D
R
G
E
H
N
N
N
N
T
V
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
E409
E
N
N
R
P
R
I
E
T
I
H
V
P
M
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
93.3
0
86.6
N.A.
40
13.3
N.A.
46.6
6.6
0
6.6
N.A.
13.3
20
13.3
0
P-Site Similarity:
100
100
20
93.3
N.A.
60
33.3
N.A.
60
26.6
6.6
20
N.A.
26.6
20
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
0
0
8
0
% A
% Cys:
0
8
0
0
0
0
8
0
36
0
0
0
0
0
0
% C
% Asp:
36
8
8
0
29
0
8
8
0
0
15
0
29
8
0
% D
% Glu:
29
0
50
0
0
0
8
15
0
0
0
8
8
8
8
% E
% Phe:
0
8
0
0
0
0
0
8
0
43
0
0
8
0
0
% F
% Gly:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
0
0
0
0
15
8
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
8
0
0
8
0
15
0
29
8
% I
% Lys:
15
0
8
0
0
29
0
8
8
8
0
0
0
0
22
% K
% Leu:
8
0
8
8
0
0
22
0
0
15
8
29
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
15
8
% M
% Asn:
0
15
15
15
0
0
8
0
0
8
8
8
22
0
0
% N
% Pro:
0
0
0
8
15
15
0
22
0
8
36
0
15
0
0
% P
% Gln:
0
0
0
0
0
0
8
8
8
0
8
0
0
8
0
% Q
% Arg:
0
36
0
15
8
15
15
0
15
0
8
0
0
0
0
% R
% Ser:
8
22
0
8
15
15
8
8
0
8
8
22
0
0
15
% S
% Thr:
0
0
0
15
8
22
0
0
8
0
8
0
8
15
0
% T
% Val:
0
0
0
29
15
8
8
0
15
8
0
22
8
8
36
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _