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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HRH1 All Species: 19.09
Human Site: T382 Identified Species: 32.31
UniProt: P35367 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35367 NP_000852.1 487 55784 T382 K L R S G S N T G L D Y I K F
Chimpanzee Pan troglodytes Q9N2B2 487 55605 T382 K L R S G S N T G L D Y I K F
Rhesus Macaque Macaca mulatta P56490 532 60122 S406 K V K I M P C S F P V A K E P
Dog Lupus familis XP_541769 536 61594 T431 K P R S E S S T G L D Y I K F
Cat Felis silvestris
Mouse Mus musculus P70174 488 55663 S383 K A R S R S N S G L D Y I K V
Rat Rattus norvegicus P31390 486 55674 S381 K S R S G S N S G L D Y I K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505379 489 54959 G384 E Q P K G P S G L G G Y L K Y
Chicken Gallus gallus P30372 466 51547 A373 V K M T K Q P A K K K P P P S
Frog Xenopus laevis P30544 484 54107 V390 A S I A R N Q V R K K R Q M A
Zebra Danio Brachydanio rerio NP_001036196 534 61056 S429 N S P P L D A S I A L P A K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IS44 506 56459 A422 K K R E K S S A K K E R K A T
Honey Bee Apis mellifera XP_395477 546 60788 S438 T Q K S N V A S Q T S P T T K
Nematode Worm Caenorhab. elegans Q18775 517 58629 Q396 N V R E K S R Q M M R Y V H E
Sea Urchin Strong. purpuratus NP_001012721 677 76342 N544 I P K A Q V K N G G V A G R F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 27 78.5 N.A. 78 78.8 N.A. 60.1 27.3 27.7 41.3 N.A. 28.6 28.3 26.8 29.2
Protein Similarity: 100 99.1 44.7 83.4 N.A. 84.6 85.6 N.A. 70.7 47.2 44.5 57.1 N.A. 48.8 43 46.8 49
P-Site Identity: 100 100 6.6 80 N.A. 73.3 80 N.A. 20 0 0 6.6 N.A. 20 6.6 20 13.3
P-Site Similarity: 100 100 33.3 86.6 N.A. 80 86.6 N.A. 46.6 6.6 13.3 13.3 N.A. 33.3 20 40 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 15 0 0 15 15 0 8 0 15 8 8 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 36 0 0 0 0 % D
% Glu: 8 0 0 15 8 0 0 0 0 0 8 0 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 29 % F
% Gly: 0 0 0 0 29 0 0 8 43 15 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 8 0 8 8 0 0 0 0 8 0 0 0 36 0 8 % I
% Lys: 50 15 22 8 22 0 8 0 15 22 15 0 15 50 8 % K
% Leu: 0 15 0 0 8 0 0 0 8 36 8 0 8 0 0 % L
% Met: 0 0 8 0 8 0 0 0 8 8 0 0 0 8 0 % M
% Asn: 15 0 0 0 8 8 29 8 0 0 0 0 0 0 0 % N
% Pro: 0 15 15 8 0 15 8 0 0 8 0 22 8 8 8 % P
% Gln: 0 15 0 0 8 8 8 8 8 0 0 0 8 0 8 % Q
% Arg: 0 0 50 0 15 0 8 0 8 0 8 15 0 8 0 % R
% Ser: 0 22 0 43 0 50 22 36 0 0 8 0 0 0 8 % S
% Thr: 8 0 0 8 0 0 0 22 0 8 0 0 8 8 8 % T
% Val: 8 15 0 0 0 15 0 8 0 0 15 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _