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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
33.94
Human Site:
T140
Identified Species:
57.44
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
T140
L
R
Y
L
K
Y
R
T
K
T
R
A
S
A
T
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
T140
L
R
Y
L
K
Y
R
T
K
T
R
A
S
A
T
Rhesus Macaque
Macaca mulatta
P56490
532
60122
T143
L
T
Y
R
A
K
R
T
P
K
R
A
G
V
M
Dog
Lupus familis
XP_541769
536
61594
T189
L
R
Y
L
K
Y
R
T
K
T
R
A
S
A
T
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
T140
L
R
Y
L
R
Y
R
T
K
T
R
A
S
A
T
Rat
Rattus norvegicus
P31390
486
55674
T140
L
R
Y
L
R
Y
R
T
K
T
R
A
S
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
S139
T
R
A
S
T
M
I
S
G
A
W
L
L
S
L
Chicken
Gallus gallus
P30372
466
51547
T139
L
T
Y
P
V
K
R
T
T
K
M
A
G
M
M
Frog
Xenopus laevis
P30544
484
54107
T146
L
T
Y
P
A
R
R
T
T
K
M
A
G
L
M
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
T164
L
Q
Y
L
K
Y
R
T
R
G
R
A
T
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
N189
I
K
Y
A
K
H
K
N
S
R
R
V
C
L
T
Honey Bee
Apis mellifera
XP_395477
546
60788
T195
A
Q
Y
R
S
W
R
T
K
N
R
V
I
W
M
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
S156
I
G
Y
R
D
K
V
S
K
R
R
I
L
M
A
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
T173
L
K
Y
M
K
K
R
T
P
R
R
A
M
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
100
40
100
N.A.
93.3
93.3
N.A.
6.6
33.3
33.3
60
N.A.
26.6
33.3
20
46.6
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
20
33.3
33.3
80
N.A.
53.3
46.6
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
15
0
0
0
0
8
0
72
0
36
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
8
8
0
0
22
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
0
0
0
8
0
0
0
0
8
8
0
0
% I
% Lys:
0
15
0
0
43
29
8
0
50
22
0
0
0
0
0
% K
% Leu:
72
0
0
43
0
0
0
0
0
0
0
8
15
29
15
% L
% Met:
0
0
0
8
0
8
0
0
0
0
15
0
8
15
36
% M
% Asn:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
15
0
0
0
0
15
0
0
0
0
0
0
% P
% Gln:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
43
0
22
15
8
79
0
8
22
79
0
0
0
0
% R
% Ser:
0
0
0
8
8
0
0
15
8
0
0
0
36
8
0
% S
% Thr:
8
22
0
0
8
0
0
79
15
36
0
0
8
0
43
% T
% Val:
0
0
0
0
8
0
8
0
0
0
0
15
0
8
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
8
0
0
8
0
% W
% Tyr:
0
0
93
0
0
43
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _