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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
14.48
Human Site:
S6
Identified Species:
24.5
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
S6
_
_
M
S
L
P
N
S
S
C
L
L
E
D
K
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
S6
_
_
M
S
L
P
N
S
S
C
L
L
E
D
K
Rhesus Macaque
Macaca mulatta
P56490
532
60122
A9
E
G
D
S
Y
H
N
A
T
T
V
N
G
T
P
Dog
Lupus familis
XP_541769
536
61594
S55
V
P
M
N
L
P
N
S
S
C
I
F
E
D
K
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
T6
_
_
M
S
L
P
N
T
S
S
A
S
E
D
K
Rat
Rattus norvegicus
P31390
486
55674
T6
_
_
M
S
F
A
N
T
S
S
T
F
E
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
E6
_
_
M
C
E
G
N
E
L
T
P
I
N
T
T
Chicken
Gallus gallus
P30372
466
51547
I7
_
M
N
N
S
T
Y
I
N
S
S
S
E
N
V
Frog
Xenopus laevis
P30544
484
54107
A12
T
W
E
N
E
S
S
A
S
N
H
S
I
D
E
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
F30
L
T
T
A
N
S
Q
F
K
R
I
D
N
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
L55
L
Y
L
D
G
Y
R
L
N
C
T
N
E
T
L
Honey Bee
Apis mellifera
XP_395477
546
60788
A61
N
G
T
I
T
G
N
A
T
T
L
S
T
A
E
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
V21
Y
I
T
M
T
P
S
V
S
T
E
N
D
T
T
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
N39
G
Y
S
G
Y
P
M
N
E
S
S
F
N
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
100
13.3
66.6
N.A.
69.2
53.8
N.A.
15.3
7.1
13.3
0
N.A.
13.3
13.3
13.3
6.6
P-Site Similarity:
100
100
40
80
N.A.
76.9
61.5
N.A.
23
28.5
40
13.3
N.A.
33.3
40
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
22
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
29
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
0
0
8
8
43
0
% D
% Glu:
8
0
8
0
15
0
0
8
8
0
8
0
50
8
15
% E
% Phe:
0
0
0
0
8
0
0
8
0
0
0
22
0
0
0
% F
% Gly:
8
15
0
8
8
15
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
8
0
8
0
0
0
8
0
0
15
8
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
36
% K
% Leu:
15
0
8
0
29
0
0
8
8
0
22
15
0
0
8
% L
% Met:
0
8
43
8
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
22
8
0
58
8
15
8
0
22
22
8
0
% N
% Pro:
0
8
0
0
0
43
0
0
0
0
8
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
8
36
8
15
15
22
50
29
15
29
0
0
8
% S
% Thr:
8
8
22
0
15
8
0
15
15
29
15
0
8
36
22
% T
% Val:
8
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
15
0
0
15
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
43
36
0
0
0
0
0
0
0
0
0
0
0
0
0
% _