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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
27.88
Human Site:
S398
Identified Species:
47.18
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
S398
W
K
R
L
R
S
H
S
R
Q
Y
V
S
G
L
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
S398
W
K
R
L
R
S
H
S
R
Q
Y
V
S
G
L
Rhesus Macaque
Macaca mulatta
P56490
532
60122
P422
T
K
G
L
N
P
N
P
S
H
Q
M
T
K
R
Dog
Lupus familis
XP_541769
536
61594
S447
W
K
R
L
R
S
H
S
R
Q
Y
V
S
G
L
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
S399
W
K
R
L
R
S
H
S
R
Q
Y
V
S
G
L
Rat
Rattus norvegicus
P31390
486
55674
S397
W
K
R
L
R
S
H
S
R
Q
Y
V
S
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
S400
W
K
R
L
R
S
H
S
R
Q
Y
L
P
A
L
Chicken
Gallus gallus
P30372
466
51547
I389
E
K
K
V
T
R
T
I
L
A
I
L
L
A
F
Frog
Xenopus laevis
P30544
484
54107
T406
R
E
K
K
V
T
R
T
I
F
A
I
L
L
A
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
S445
W
Q
K
L
C
E
Q
S
K
Q
S
I
H
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
V438
T
L
A
I
V
L
G
V
F
L
F
C
W
L
P
Honey Bee
Apis mellifera
XP_395477
546
60788
S454
Q
R
R
D
P
L
L
S
R
Q
K
S
R
T
E
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
I412
R
A
A
R
T
L
S
I
V
V
G
A
F
I
L
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
H560
F
A
R
F
S
I
R
H
G
K
T
S
E
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
80
6.6
0
26.6
N.A.
0
26.6
6.6
13.3
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
86.6
26.6
33.3
60
N.A.
13.3
33.3
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
15
0
0
0
0
0
0
8
8
8
0
15
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
8
0
0
0
0
0
0
8
0
8
% E
% Phe:
8
0
0
8
0
0
0
0
8
8
8
0
8
8
8
% F
% Gly:
0
0
8
0
0
0
8
0
8
0
8
0
0
36
0
% G
% His:
0
0
0
0
0
0
43
8
0
8
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
8
0
15
8
0
8
15
0
8
0
% I
% Lys:
0
58
22
8
0
0
0
0
8
8
8
0
0
8
0
% K
% Leu:
0
8
0
58
0
22
8
0
8
8
0
15
15
15
58
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
8
0
8
0
0
0
0
8
0
8
% P
% Gln:
8
8
0
0
0
0
8
0
0
58
8
0
0
0
0
% Q
% Arg:
15
8
58
8
43
8
15
0
50
0
0
0
8
0
8
% R
% Ser:
0
0
0
0
8
43
8
58
8
0
8
15
36
8
0
% S
% Thr:
15
0
0
0
15
8
8
8
0
0
8
0
8
8
0
% T
% Val:
0
0
0
8
15
0
0
8
8
8
0
36
0
0
0
% V
% Trp:
50
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
43
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _