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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
11.21
Human Site:
S327
Identified Species:
18.97
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
S327
D
Y
V
A
V
N
R
S
H
G
Q
L
K
T
D
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
S327
D
Y
V
A
V
N
Q
S
H
G
Q
L
K
T
D
Rhesus Macaque
Macaca mulatta
P56490
532
60122
T351
E
T
F
V
K
A
Q
T
E
K
H
D
S
D
T
Dog
Lupus familis
XP_541769
536
61594
S376
S
Y
V
A
I
N
Q
S
Q
S
M
L
E
M
D
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
S328
K
A
N
D
Q
T
L
S
Q
P
K
M
D
E
Q
Rat
Rattus norvegicus
P31390
486
55674
S326
K
A
N
D
Q
A
L
S
Q
P
K
M
D
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
R329
G
E
S
V
P
A
K
R
D
Q
P
S
Q
E
N
Chicken
Gallus gallus
P30372
466
51547
L318
I
S
A
S
Q
D
H
L
K
V
E
N
S
K
L
Frog
Xenopus laevis
P30544
484
54107
T335
P
L
P
A
K
A
N
T
A
S
K
W
S
K
I
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
Q374
S
E
N
T
A
Q
P
Q
T
F
I
N
V
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
V367
A
M
K
P
L
S
F
V
R
Y
G
V
Q
E
A
Honey Bee
Apis mellifera
XP_395477
546
60788
A383
I
R
K
R
S
S
L
A
G
L
V
A
Q
T
G
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
Q341
D
S
I
S
R
S
S
Q
R
N
F
R
G
R
N
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
P489
A
S
K
E
E
L
E
P
L
R
R
N
S
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
93.3
0
46.6
N.A.
6.6
6.6
N.A.
0
0
6.6
6.6
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
20
66.6
N.A.
20
20
N.A.
20
20
20
13.3
N.A.
26.6
26.6
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
8
29
8
29
0
8
8
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
0
0
15
0
8
0
0
8
0
0
8
15
8
36
% D
% Glu:
8
15
0
8
8
0
8
0
8
0
8
0
8
29
0
% E
% Phe:
0
0
8
0
0
0
8
0
0
8
8
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
15
8
0
8
0
8
% G
% His:
0
0
0
0
0
0
8
0
15
0
8
0
0
0
0
% H
% Ile:
15
0
8
0
8
0
0
0
0
0
8
0
0
0
8
% I
% Lys:
15
0
22
0
15
0
8
0
8
8
22
0
15
15
0
% K
% Leu:
0
8
0
0
8
8
22
8
8
8
0
22
0
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
8
15
0
8
0
% M
% Asn:
0
0
22
0
0
22
8
0
0
8
0
22
0
0
15
% N
% Pro:
8
0
8
8
8
0
8
8
0
15
8
0
0
0
0
% P
% Gln:
0
0
0
0
22
8
22
15
22
8
15
0
22
0
15
% Q
% Arg:
0
8
0
8
8
0
8
8
15
8
8
8
0
8
0
% R
% Ser:
15
22
8
15
8
22
8
36
0
15
0
8
29
8
0
% S
% Thr:
0
8
0
8
0
8
0
15
8
0
0
0
0
22
8
% T
% Val:
0
0
22
15
15
0
0
8
0
8
8
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
22
0
0
0
0
0
0
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _