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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
12.73
Human Site:
S277
Identified Species:
21.54
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
S277
G
S
V
L
K
S
P
S
Q
T
P
K
E
M
K
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
S277
G
S
V
L
K
S
P
S
Q
T
X
K
E
M
K
Rhesus Macaque
Macaca mulatta
P56490
532
60122
A295
T
D
P
S
T
N
Q
A
K
A
E
Q
L
T
T
Dog
Lupus familis
XP_541769
536
61594
S326
E
P
V
L
K
P
P
S
Q
D
S
E
E
M
K
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
T276
G
G
L
D
Q
K
S
T
S
E
D
P
K
V
T
Rat
Rattus norvegicus
P31390
486
55674
T276
V
G
L
D
Q
K
S
T
S
E
D
P
K
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
A280
L
Q
P
A
E
K
S
A
K
V
V
I
K
E
Q
Chicken
Gallus gallus
P30372
466
51547
T269
K
V
Q
N
G
K
T
T
G
E
S
V
M
E
N
Frog
Xenopus laevis
P30544
484
54107
L284
I
E
K
S
M
T
N
L
Q
T
A
E
E
K
E
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
E310
Y
N
S
R
E
N
T
E
E
M
T
S
E
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
S318
E
A
A
T
N
T
A
S
G
S
N
E
E
E
D
Honey Bee
Apis mellifera
XP_395477
546
60788
D332
S
G
T
M
G
V
T
D
S
T
E
K
Q
T
G
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
R289
S
S
S
L
R
N
S
R
F
H
A
R
E
S
T
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
A385
R
I
L
K
R
K
R
A
E
K
E
A
L
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
93.3
0
60
N.A.
6.6
6.6
N.A.
0
0
20
13.3
N.A.
13.3
13.3
20
0
P-Site Similarity:
100
93.3
26.6
66.6
N.A.
40
33.3
N.A.
33.3
6.6
40
40
N.A.
40
26.6
40
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
0
8
22
0
8
15
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
15
0
0
0
8
0
8
15
0
0
0
8
% D
% Glu:
15
8
0
0
15
0
0
8
15
22
22
22
50
22
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
22
22
0
0
15
0
0
0
15
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
8
0
8
8
22
36
0
0
15
8
0
22
22
8
29
% K
% Leu:
8
0
22
29
0
0
0
8
0
0
0
0
15
0
0
% L
% Met:
0
0
0
8
8
0
0
0
0
8
0
0
8
29
0
% M
% Asn:
0
8
0
8
8
22
8
0
0
0
8
0
0
0
8
% N
% Pro:
0
8
15
0
0
8
22
0
0
0
8
15
0
8
0
% P
% Gln:
0
8
8
0
15
0
8
0
29
0
0
8
8
0
8
% Q
% Arg:
8
0
0
8
15
0
8
8
0
0
0
8
0
0
0
% R
% Ser:
15
22
15
15
0
15
29
29
22
8
15
8
0
8
0
% S
% Thr:
8
0
8
8
8
15
22
22
0
29
8
0
0
15
29
% T
% Val:
8
8
22
0
0
8
0
0
0
8
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _