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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
21.52
Human Site:
S233
Identified Species:
36.41
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
S233
L
I
N
R
S
L
P
S
F
S
E
I
K
L
R
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
S233
L
I
N
G
S
L
P
S
F
S
E
I
K
L
R
Rhesus Macaque
Macaca mulatta
P56490
532
60122
R251
P
A
H
R
A
L
F
R
S
C
L
R
C
P
R
Dog
Lupus familis
XP_541769
536
61594
S282
L
I
N
G
S
L
P
S
F
S
E
P
K
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
T233
L
T
N
G
S
L
P
T
F
L
E
I
K
L
R
Rat
Rattus norvegicus
P31390
486
55674
S233
L
T
N
G
S
L
P
S
F
S
E
L
K
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
T237
M
Q
D
K
K
V
C
T
K
K
Q
K
K
K
P
Chicken
Gallus gallus
P30372
466
51547
Q231
K
K
E
A
A
Q
N
Q
D
P
V
S
P
S
L
Frog
Xenopus laevis
P30544
484
54107
S244
E
K
K
K
P
I
S
S
M
K
S
L
L
I
K
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
N267
D
A
T
D
T
L
T
N
G
L
Q
L
Q
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
G280
P
H
L
S
E
L
T
G
G
S
V
I
E
N
I
Honey Bee
Apis mellifera
XP_395477
546
60788
A291
R
K
M
Q
S
M
V
A
L
S
A
G
A
I
Q
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
K249
I
K
T
V
S
I
K
K
R
N
G
K
K
S
N
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
T320
S
L
S
T
S
K
D
T
S
Q
E
Y
A
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
93.3
20
80
N.A.
73.3
80
N.A.
6.6
0
6.6
6.6
N.A.
20
13.3
13.3
13.3
P-Site Similarity:
100
93.3
33.3
86.6
N.A.
80
86.6
N.A.
46.6
6.6
40
46.6
N.A.
26.6
46.6
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
15
0
0
8
0
0
8
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
0
0
8
0
0
% C
% Asp:
8
0
8
8
0
0
8
0
8
0
0
0
0
8
0
% D
% Glu:
8
0
8
0
8
0
0
0
0
0
43
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
36
0
0
0
0
0
0
% F
% Gly:
0
0
0
29
0
0
0
8
15
0
8
8
0
0
0
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
22
0
0
0
15
0
0
0
0
0
29
0
22
8
% I
% Lys:
8
29
8
15
8
8
8
8
8
15
0
15
50
8
15
% K
% Leu:
36
8
8
0
0
58
0
0
8
15
8
22
8
36
8
% L
% Met:
8
0
8
0
0
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
36
0
0
0
8
8
0
8
0
0
0
8
8
% N
% Pro:
15
0
0
0
8
0
36
0
0
8
0
8
8
8
8
% P
% Gln:
0
8
0
8
0
8
0
8
0
8
15
0
8
0
15
% Q
% Arg:
8
0
0
15
0
0
0
8
8
0
0
8
0
0
36
% R
% Ser:
8
0
8
8
58
0
8
36
15
43
8
8
0
15
0
% S
% Thr:
0
15
15
8
8
0
15
22
0
0
0
0
0
0
8
% T
% Val:
0
0
0
8
0
8
8
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _