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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
31.82
Human Site:
S128
Identified Species:
53.85
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
S128
L
C
I
D
R
Y
R
S
V
Q
Q
P
L
R
Y
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
S128
L
C
I
D
R
Y
R
S
V
Q
Q
P
L
R
Y
Rhesus Macaque
Macaca mulatta
P56490
532
60122
S131
I
S
F
D
R
Y
F
S
I
T
R
P
L
T
Y
Dog
Lupus familis
XP_541769
536
61594
S177
L
C
I
D
R
Y
R
S
V
R
Q
P
L
R
Y
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
S128
L
C
I
D
R
Y
R
S
V
Q
Q
P
L
R
Y
Rat
Rattus norvegicus
P31390
486
55674
S128
L
C
I
D
R
Y
R
S
V
Q
Q
P
L
R
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
K127
Q
Q
P
L
K
Y
L
K
Y
R
T
K
T
R
A
Chicken
Gallus gallus
P30372
466
51547
C127
I
S
F
D
R
Y
F
C
V
T
K
P
L
T
Y
Frog
Xenopus laevis
P30544
484
54107
C134
I
S
L
E
R
X
F
C
V
T
K
P
L
T
Y
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
S152
L
C
L
D
R
Y
R
S
V
R
H
P
L
Q
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
A177
I
S
I
D
R
Y
I
A
V
T
Q
P
I
K
Y
Honey Bee
Apis mellifera
XP_395477
546
60788
S183
I
T
I
D
R
F
C
S
V
K
I
A
A
Q
Y
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
A144
I
S
L
D
R
Y
M
A
G
Q
D
P
I
G
Y
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
S161
L
S
L
D
R
Y
W
S
I
S
S
P
L
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
100
46.6
93.3
N.A.
100
100
N.A.
13.3
46.6
33.3
73.3
N.A.
53.3
40
40
53.3
P-Site Similarity:
100
100
66.6
100
N.A.
100
100
N.A.
26.6
60
60
93.3
N.A.
80
66.6
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
15
0
0
0
8
8
0
8
% A
% Cys:
0
43
0
0
0
0
8
15
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
86
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
15
0
0
8
22
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
43
0
50
0
0
0
8
0
15
0
8
0
15
0
0
% I
% Lys:
0
0
0
0
8
0
0
8
0
8
15
8
0
15
0
% K
% Leu:
50
0
29
8
0
0
8
0
0
0
0
0
72
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
86
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
36
43
0
0
15
0
% Q
% Arg:
0
0
0
0
93
0
43
0
0
22
8
0
0
43
0
% R
% Ser:
0
43
0
0
0
0
0
65
0
8
8
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
29
8
0
8
22
0
% T
% Val:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
86
0
0
8
0
0
0
0
0
93
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _