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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA1A
All Species:
23.94
Human Site:
S265
Identified Species:
58.52
UniProt:
P35348
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35348
NP_000671.2
466
51487
S265
S
V
R
L
L
K
F
S
R
E
K
K
A
A
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
NP_001108205
466
51398
S265
S
V
R
L
L
K
F
S
R
E
K
K
A
A
K
Dog
Lupus familis
XP_534567
466
51508
S265
S
V
R
L
L
K
F
S
R
E
K
K
A
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P97718
466
51744
S265
S
V
R
L
L
K
F
S
R
E
K
K
A
A
K
Rat
Rattus norvegicus
P43140
466
51579
S265
S
V
R
L
L
K
F
S
R
E
K
K
A
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520086
428
47465
R244
V
T
L
R
I
H
R
R
N
V
P
E
A
R
G
Chicken
Gallus gallus
XP_425762
467
51190
S265
S
V
R
L
L
K
F
S
R
E
K
K
A
A
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001338938
478
52644
R272
L
R
L
L
K
F
S
R
E
K
K
A
A
K
T
Tiger Blowfish
Takifugu rubipres
O42385
423
46982
V239
R
F
R
I
R
K
T
V
K
K
T
E
K
A
K
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203873
574
63580
S280
K
R
Q
N
S
A
N
S
L
L
R
P
S
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.2
92.9
N.A.
91.8
92.6
N.A.
56.6
77
N.A.
58.7
25.1
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
N.A.
98.9
96.3
N.A.
95.4
96.1
N.A.
66.9
86.7
N.A.
73.6
44.8
N.A.
N.A.
N.A.
49.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
100
N.A.
20
26.6
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
100
N.A.
26.6
53.3
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
10
80
70
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
60
0
20
0
0
0
% E
% Phe:
0
10
0
0
0
10
60
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
70
0
0
10
20
70
60
10
10
70
% K
% Leu:
10
0
20
70
60
0
0
0
10
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
20
70
10
10
0
10
20
60
0
10
0
0
20
0
% R
% Ser:
60
0
0
0
10
0
10
70
0
0
0
0
10
0
0
% S
% Thr:
0
10
0
0
0
0
10
0
0
0
10
0
0
0
20
% T
% Val:
10
60
0
0
0
0
0
10
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _