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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCGF2 All Species: 14.24
Human Site: S289 Identified Species: 31.33
UniProt: P35227 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35227 NP_009075.1 344 37788 S289 P S H G S P S S H G P P A T H
Chimpanzee Pan troglodytes XP_511440 344 37774 S289 P S H G S P S S H G P P A T H
Rhesus Macaque Macaca mulatta XP_001083705 344 37727 S289 P S H G S P S S H G P P A T H
Dog Lupus familis XP_849338 326 36889 L272 A P S T S S C L P S P S T P V
Cat Felis silvestris
Mouse Mus musculus P23798 342 37704 S288 T P S H G S P S S H G P P A T
Rat Rattus norvegicus Q6DLV9 243 28763 R189 A E V R H L R R V L C H R L M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511592 326 36991 L272 I P S T S S C L P S P S T P V
Chicken Gallus gallus Q5SDR3 326 36866 L272 L P S T S S C L P S P S T P V
Frog Xenopus laevis Q640D5 323 36554 T269 L G G G I P S T S S C M P R P
Zebra Danio Brachydanio rerio Q8JIR0 320 36520 S266 P A G V P S T S S P L P S P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783799 358 38036 S294 G A T T L K S S C G P I N G K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 99.1 62.2 N.A. 95.3 31.3 N.A. 63 63.9 61 61.9 N.A. N.A. N.A. N.A. 34
Protein Similarity: 100 99.4 99.4 76.7 N.A. 96.5 43.9 N.A. 77 77.6 74.1 74.7 N.A. N.A. N.A. N.A. 48.6
P-Site Identity: 100 100 100 13.3 N.A. 13.3 0 N.A. 13.3 13.3 20 20 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 100 13.3 N.A. 13.3 0 N.A. 13.3 13.3 26.6 40 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 19 0 0 0 0 0 0 0 0 0 0 28 10 0 % A
% Cys: 0 0 0 0 0 0 28 0 10 0 19 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 19 37 10 0 0 0 0 37 10 0 0 10 0 % G
% His: 0 0 28 10 10 0 0 0 28 10 0 10 0 0 28 % H
% Ile: 10 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % K
% Leu: 19 0 0 0 10 10 0 28 0 10 10 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 37 37 0 0 10 37 10 0 28 10 64 46 19 37 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 0 0 10 10 0 0 0 0 10 10 0 % R
% Ser: 0 28 37 0 55 46 46 55 28 37 0 28 10 0 10 % S
% Thr: 10 0 10 37 0 0 10 10 0 0 0 0 28 28 10 % T
% Val: 0 0 10 10 0 0 0 0 10 0 0 0 0 0 28 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _