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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNNA1
All Species:
44.24
Human Site:
Y419
Identified Species:
74.87
UniProt:
P35221
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35221
NP_001894.2
906
100071
Y419
N
E
K
E
V
K
E
Y
A
Q
V
F
R
E
H
Chimpanzee
Pan troglodytes
XP_001172018
906
100083
Y419
N
E
K
E
V
K
E
Y
A
Q
V
F
R
E
H
Rhesus Macaque
Macaca mulatta
XP_001112889
963
107071
Y451
N
E
K
E
V
K
E
Y
A
Q
V
F
R
E
H
Dog
Lupus familis
XP_540203
909
100744
Y417
N
E
K
E
V
K
E
Y
A
Q
V
F
R
E
H
Cat
Felis silvestris
Mouse
Mus musculus
P26231
906
100088
Y419
N
E
K
E
V
K
E
Y
A
Q
V
F
R
E
H
Rat
Rattus norvegicus
NP_001007146
908
100218
Y421
N
E
K
E
V
K
E
Y
A
Q
V
F
R
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516414
732
81211
P293
D
K
Q
I
I
V
D
P
L
S
F
S
E
E
R
Chicken
Gallus gallus
P30997
906
100673
Y418
N
E
K
E
V
K
E
Y
A
Q
V
F
R
E
H
Frog
Xenopus laevis
Q6GLP0
966
107082
Y429
N
E
K
E
V
K
E
Y
A
Q
V
F
R
E
H
Zebra Danio
Brachydanio rerio
B7ZC77
865
95838
Y377
N
E
K
E
V
K
E
Y
A
Q
V
F
R
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35220
917
102426
K422
N
E
K
K
V
R
E
K
S
E
I
F
T
K
H
Honey Bee
Apis mellifera
XP_625229
909
101515
Y415
R
D
K
E
V
E
E
Y
A
L
V
F
T
E
H
Nematode Worm
Caenorhab. elegans
P90947
927
103976
R413
H
E
E
N
T
R
Y
R
S
K
M
F
Q
E
H
Sea Urchin
Strong. purpuratus
XP_784341
911
102424
Y418
N
E
A
E
V
E
K
Y
A
K
V
F
Q
E
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
76.9
81
N.A.
99.4
99.2
N.A.
76.9
81.6
76.1
79
N.A.
61.5
64.9
37.7
63.6
Protein Similarity:
100
99.8
85.6
90
N.A.
99.7
99.5
N.A.
78.9
90.5
84.7
87.9
N.A.
78.4
80.6
59.7
80.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
100
100
N.A.
46.6
66.6
26.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
100
100
100
N.A.
86.6
80
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
79
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
86
8
79
0
15
79
0
0
8
0
0
8
93
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
93
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
93
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
8
79
8
0
65
8
8
0
15
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
79
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
65
0
0
15
0
0
% Q
% Arg:
8
0
0
0
0
15
0
8
0
0
0
0
65
0
8
% R
% Ser:
0
0
0
0
0
0
0
0
15
8
0
8
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
0
15
0
0
% T
% Val:
0
0
0
0
86
8
0
0
0
0
79
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
79
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _