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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNNA1
All Species:
9.09
Human Site:
Y222
Identified Species:
15.38
UniProt:
P35221
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35221
NP_001894.2
906
100071
Y222
Q
K
N
V
P
I
L
Y
T
A
S
Q
A
C
L
Chimpanzee
Pan troglodytes
XP_001172018
906
100083
Y222
Q
K
N
V
P
I
L
Y
T
A
S
Q
A
C
L
Rhesus Macaque
Macaca mulatta
XP_001112889
963
107071
L254
L
K
K
N
A
T
M
L
Y
T
A
S
Q
A
F
Dog
Lupus familis
XP_540203
909
100744
L220
L
K
K
N
A
T
M
L
Y
T
A
S
Q
A
F
Cat
Felis silvestris
Mouse
Mus musculus
P26231
906
100088
Y222
Q
K
N
V
P
I
L
Y
T
A
S
Q
A
C
L
Rat
Rattus norvegicus
NP_001007146
908
100218
A224
N
V
P
I
L
Y
T
A
S
Q
A
C
L
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516414
732
81211
D113
S
A
S
G
E
F
A
D
D
P
C
S
S
M
K
Chicken
Gallus gallus
P30997
906
100673
L220
L
K
K
N
A
T
M
L
Y
T
A
S
Q
A
F
Frog
Xenopus laevis
Q6GLP0
966
107082
L220
L
K
K
N
A
T
M
L
Y
T
A
S
Q
A
F
Zebra Danio
Brachydanio rerio
B7ZC77
865
95838
L180
L
K
K
N
A
T
M
L
Y
T
A
S
Q
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35220
917
102426
M225
M
L
K
K
H
S
T
M
L
L
T
A
S
K
V
Honey Bee
Apis mellifera
XP_625229
909
101515
L218
L
K
K
H
S
T
M
L
L
T
A
S
K
V
Y
Nematode Worm
Caenorhab. elegans
P90947
927
103976
L216
L
R
Q
T
A
P
L
L
Y
T
S
T
R
T
F
Sea Urchin
Strong. purpuratus
XP_784341
911
102424
L221
L
R
K
H
S
T
M
L
F
T
A
S
K
A
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
76.9
81
N.A.
99.4
99.2
N.A.
76.9
81.6
76.1
79
N.A.
61.5
64.9
37.7
63.6
Protein Similarity:
100
99.8
85.6
90
N.A.
99.7
99.5
N.A.
78.9
90.5
84.7
87.9
N.A.
78.4
80.6
59.7
80.9
P-Site Identity:
100
100
6.6
6.6
N.A.
100
0
N.A.
0
6.6
6.6
6.6
N.A.
0
6.6
13.3
0
P-Site Similarity:
100
100
20
20
N.A.
100
20
N.A.
13.3
20
20
20
N.A.
20
20
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
43
0
8
8
0
22
58
8
22
43
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
8
0
22
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
43
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
15
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
0
22
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
65
58
8
0
0
0
0
0
0
0
0
15
8
8
% K
% Leu:
58
8
0
0
8
0
29
58
15
8
0
0
8
0
22
% L
% Met:
8
0
0
0
0
0
50
8
0
0
0
0
0
8
0
% M
% Asn:
8
0
22
36
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
22
8
0
0
0
8
0
0
0
0
0
% P
% Gln:
22
0
8
0
0
0
0
0
0
8
0
22
36
8
0
% Q
% Arg:
0
15
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
8
0
15
8
0
0
8
0
29
58
15
0
0
% S
% Thr:
0
0
0
8
0
50
15
0
22
58
8
8
0
8
0
% T
% Val:
0
8
0
22
0
0
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
8
0
22
43
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _