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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNNA1
All Species:
52.73
Human Site:
T499
Identified Species:
89.23
UniProt:
P35221
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35221
NP_001894.2
906
100071
T499
E
K
Q
V
R
V
L
T
D
A
V
D
D
I
T
Chimpanzee
Pan troglodytes
XP_001172018
906
100083
T499
E
K
Q
V
R
V
L
T
D
A
V
D
D
I
T
Rhesus Macaque
Macaca mulatta
XP_001112889
963
107071
T531
E
K
Q
V
R
V
L
T
E
A
V
D
D
I
T
Dog
Lupus familis
XP_540203
909
100744
T497
E
K
Q
V
R
V
L
T
E
A
V
D
D
I
T
Cat
Felis silvestris
Mouse
Mus musculus
P26231
906
100088
T499
E
K
Q
V
R
V
L
T
D
A
V
D
D
I
T
Rat
Rattus norvegicus
NP_001007146
908
100218
T501
E
K
Q
V
R
V
L
T
D
A
V
D
D
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516414
732
81211
N354
L
L
S
E
Y
M
G
N
A
G
R
K
E
R
S
Chicken
Gallus gallus
P30997
906
100673
T498
E
K
Q
V
R
V
L
T
E
A
V
D
D
I
T
Frog
Xenopus laevis
Q6GLP0
966
107082
T509
E
K
Q
V
R
V
L
T
E
A
V
D
D
I
T
Zebra Danio
Brachydanio rerio
B7ZC77
865
95838
T457
E
K
Q
V
R
I
L
T
E
A
V
D
D
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35220
917
102426
T502
E
V
Q
V
R
I
L
T
E
A
V
D
D
I
T
Honey Bee
Apis mellifera
XP_625229
909
101515
T495
E
N
Q
V
R
V
L
T
E
A
V
D
D
I
T
Nematode Worm
Caenorhab. elegans
P90947
927
103976
T493
F
D
K
V
R
L
L
T
T
A
L
D
N
I
T
Sea Urchin
Strong. purpuratus
XP_784341
911
102424
T498
E
T
Q
V
R
L
L
T
E
A
V
D
E
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
76.9
81
N.A.
99.4
99.2
N.A.
76.9
81.6
76.1
79
N.A.
61.5
64.9
37.7
63.6
Protein Similarity:
100
99.8
85.6
90
N.A.
99.7
99.5
N.A.
78.9
90.5
84.7
87.9
N.A.
78.4
80.6
59.7
80.9
P-Site Identity:
100
100
93.3
93.3
N.A.
100
100
N.A.
0
93.3
93.3
86.6
N.A.
80
86.6
53.3
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
93.3
93.3
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
93
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
29
0
0
93
79
0
0
% D
% Glu:
86
0
0
8
0
0
0
0
58
0
0
0
15
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
0
0
0
0
0
0
0
93
0
% I
% Lys:
0
65
8
0
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
8
8
0
0
0
15
93
0
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
86
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
93
0
0
0
0
0
8
0
0
8
0
% R
% Ser:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% S
% Thr:
0
8
0
0
0
0
0
93
8
0
0
0
0
0
93
% T
% Val:
0
8
0
93
0
65
0
0
0
0
86
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _