KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4
All Species:
34.24
Human Site:
Y709
Identified Species:
57.95
UniProt:
P34932
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34932
NP_002145.3
840
94331
Y709
L
G
K
Q
I
Q
Q
Y
M
K
I
I
S
S
F
Chimpanzee
Pan troglodytes
XP_517930
840
94350
Y709
L
G
K
Q
I
Q
Q
Y
M
K
I
I
S
S
F
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
Y709
L
G
K
Q
I
Q
Q
Y
M
K
I
I
S
S
F
Dog
Lupus familis
XP_533297
840
94621
V713
L
G
K
K
I
Q
L
V
M
K
V
I
E
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q61316
841
94114
Y710
L
G
K
Q
I
Q
Q
Y
M
K
V
I
S
S
F
Rat
Rattus norvegicus
O88600
840
94038
Y709
L
G
K
Q
I
Q
Q
Y
M
K
V
I
S
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
Y703
L
G
K
Q
I
Q
L
Y
M
K
I
I
S
S
F
Chicken
Gallus gallus
XP_414655
840
94222
Y709
L
G
K
Q
I
Q
Q
Y
M
K
T
V
H
A
F
Frog
Xenopus laevis
P02827
647
70897
S545
D
A
K
N
A
L
E
S
Y
A
F
N
L
K
S
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
Y711
L
G
R
Q
L
Q
Q
Y
M
K
I
V
E
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
A671
S
I
M
R
V
R
K
A
Y
E
D
Y
A
N
G
Sea Urchin
Strong. purpuratus
Q06068
889
98600
Y744
F
G
K
A
L
V
P
Y
I
K
T
L
D
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
S590
A
K
L
D
D
E
Y
S
D
F
A
S
D
A
E
Red Bread Mold
Neurospora crassa
O74225
707
78655
I605
S
E
E
E
K
E
K
I
R
A
K
L
M
E
V
Conservation
Percent
Protein Identity:
100
99.7
99.5
63.9
N.A.
95.8
95.8
N.A.
87
85.9
27.8
73.2
N.A.
N.A.
N.A.
42
50.2
Protein Similarity:
100
99.7
99.7
79.6
N.A.
97.8
98.2
N.A.
92.3
93.2
46.1
85.8
N.A.
N.A.
N.A.
59.1
67.2
P-Site Identity:
100
100
100
53.3
N.A.
93.3
93.3
N.A.
93.3
73.3
6.6
60
N.A.
N.A.
N.A.
0
26.6
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
93.3
86.6
13.3
93.3
N.A.
N.A.
N.A.
46.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.5
38.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.5
55
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
8
0
0
8
0
15
8
0
8
29
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
8
0
0
0
8
0
8
0
15
0
0
% D
% Glu:
0
8
8
8
0
15
8
0
0
8
0
0
15
8
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
8
8
0
0
0
50
% F
% Gly:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
58
0
0
8
8
0
36
50
0
0
0
% I
% Lys:
0
8
72
8
8
0
15
0
0
72
8
0
0
8
0
% K
% Leu:
65
0
8
0
15
8
15
0
0
0
0
15
8
8
0
% L
% Met:
0
0
8
0
0
0
0
0
65
0
0
0
8
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
58
0
65
50
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
8
0
8
0
0
8
0
0
0
0
0
0
% R
% Ser:
15
0
0
0
0
0
0
15
0
0
0
8
43
43
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% T
% Val:
0
0
0
0
8
8
0
8
0
0
22
15
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
65
15
0
0
8
0
0
22
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _