KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4
All Species:
40.3
Human Site:
Y252
Identified Species:
68.21
UniProt:
P34932
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34932
NP_002145.3
840
94331
Y252
C
E
E
F
G
K
K
Y
K
L
D
I
K
S
K
Chimpanzee
Pan troglodytes
XP_517930
840
94350
Y252
C
E
E
F
G
K
K
Y
K
L
D
I
K
S
K
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
Y252
C
E
E
F
G
K
K
Y
K
L
D
I
K
S
K
Dog
Lupus familis
XP_533297
840
94621
Y252
C
E
E
F
K
T
K
Y
K
I
N
V
K
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61316
841
94114
Y252
C
E
E
F
G
K
K
Y
K
L
D
I
K
S
K
Rat
Rattus norvegicus
O88600
840
94038
Y252
C
E
E
F
G
K
K
Y
K
L
D
I
K
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
Y246
C
E
E
F
G
K
K
Y
K
L
D
I
K
S
K
Chicken
Gallus gallus
XP_414655
840
94222
Y252
C
E
E
F
G
K
K
Y
K
L
D
I
K
S
K
Frog
Xenopus laevis
P02827
647
70897
L136
K
E
T
A
E
A
Y
L
G
H
P
V
T
N
A
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
Y252
C
E
E
F
V
V
K
Y
K
L
D
A
K
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
Y254
R
K
E
F
K
T
K
Y
G
I
D
A
A
T
S
Sea Urchin
Strong. purpuratus
Q06068
889
98600
Y252
A
V
D
F
Q
T
R
Y
K
M
D
V
K
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
S181
D
V
T
A
A
A
V
S
Y
G
V
F
K
N
D
Red Bread Mold
Neurospora crassa
O74225
707
78655
R196
G
P
E
E
K
P
R
R
V
A
F
V
D
V
G
Conservation
Percent
Protein Identity:
100
99.7
99.5
63.9
N.A.
95.8
95.8
N.A.
87
85.9
27.8
73.2
N.A.
N.A.
N.A.
42
50.2
Protein Similarity:
100
99.7
99.7
79.6
N.A.
97.8
98.2
N.A.
92.3
93.2
46.1
85.8
N.A.
N.A.
N.A.
59.1
67.2
P-Site Identity:
100
100
100
53.3
N.A.
100
100
N.A.
100
100
6.6
73.3
N.A.
N.A.
N.A.
33.3
40
P-Site Similarity:
100
100
100
73.3
N.A.
100
100
N.A.
100
100
20
80
N.A.
N.A.
N.A.
53.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.5
38.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.5
55
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
15
8
15
0
0
0
8
0
15
8
0
8
% A
% Cys:
65
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
0
0
0
72
0
8
0
8
% D
% Glu:
0
72
79
8
8
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
79
0
0
0
0
0
0
8
8
0
0
0
% F
% Gly:
8
0
0
0
50
0
0
0
15
8
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
15
0
50
0
0
0
% I
% Lys:
8
8
0
0
22
50
72
0
72
0
0
0
79
0
58
% K
% Leu:
0
0
0
0
0
0
0
8
0
58
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
15
15
% N
% Pro:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
15
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
0
0
0
0
0
58
8
% S
% Thr:
0
0
15
0
0
22
0
0
0
0
0
0
8
15
0
% T
% Val:
0
15
0
0
8
8
8
0
8
0
8
29
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
79
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _