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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA4
All Species:
35.45
Human Site:
Y184
Identified Species:
60
UniProt:
P34932
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34932
NP_002145.3
840
94331
Y184
V
A
L
A
Y
G
I
Y
K
Q
D
L
P
A
L
Chimpanzee
Pan troglodytes
XP_517930
840
94350
Y184
V
A
L
A
Y
G
I
Y
K
Q
D
L
P
A
L
Rhesus Macaque
Macaca mulatta
XP_001106968
840
94362
Y184
V
A
L
A
Y
G
I
Y
K
Q
D
L
P
A
L
Dog
Lupus familis
XP_533297
840
94621
Y184
V
A
L
A
Y
G
I
Y
K
Q
D
L
P
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61316
841
94114
Y184
V
A
L
A
Y
G
I
Y
K
Q
D
L
P
A
L
Rat
Rattus norvegicus
O88600
840
94038
Y184
V
A
L
A
Y
G
I
Y
K
Q
D
L
P
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510127
834
93982
A184
I
Y
K
Q
D
L
P
A
L
E
E
K
P
R
N
Chicken
Gallus gallus
XP_414655
840
94222
Y184
V
A
L
A
Y
G
I
Y
K
Q
D
L
P
A
L
Frog
Xenopus laevis
P02827
647
70897
P82
I
G
R
K
F
N
D
P
V
V
Q
C
D
L
K
Zebra Danio
Brachydanio rerio
NP_956151
840
94728
Y184
V
A
L
A
Y
G
I
Y
K
Q
D
L
P
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q05036
776
86878
G184
T
A
I
A
L
A
Y
G
I
Y
K
Q
D
L
P
Sea Urchin
Strong. purpuratus
Q06068
889
98600
Y184
V
A
L
A
Y
G
I
Y
K
Q
D
L
P
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32590
693
77602
K127
A
M
F
I
D
K
V
K
H
T
V
Q
E
E
T
Red Bread Mold
Neurospora crassa
O74225
707
78655
S142
A
V
Q
E
L
V
L
S
V
P
A
W
F
T
D
Conservation
Percent
Protein Identity:
100
99.7
99.5
63.9
N.A.
95.8
95.8
N.A.
87
85.9
27.8
73.2
N.A.
N.A.
N.A.
42
50.2
Protein Similarity:
100
99.7
99.7
79.6
N.A.
97.8
98.2
N.A.
92.3
93.2
46.1
85.8
N.A.
N.A.
N.A.
59.1
67.2
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
100
0
93.3
N.A.
N.A.
N.A.
13.3
86.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
26.6
100
13.3
93.3
N.A.
N.A.
N.A.
20
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.5
38.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.5
55
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
72
0
72
0
8
0
8
0
0
8
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
15
0
8
0
0
0
65
0
15
0
8
% D
% Glu:
0
0
0
8
0
0
0
0
0
8
8
0
8
8
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
65
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
15
0
8
8
0
0
65
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
8
0
8
65
0
8
8
0
0
8
% K
% Leu:
0
0
65
0
15
8
8
0
8
0
0
65
0
15
50
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
8
8
0
8
0
0
72
8
22
% P
% Gln:
0
0
8
8
0
0
0
0
0
65
8
15
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
0
0
15
8
% T
% Val:
65
8
0
0
0
8
8
0
15
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
8
0
0
65
0
8
65
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _