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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHMT2
All Species:
16.82
Human Site:
Y3
Identified Species:
28.46
UniProt:
P34897
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34897
NP_005403.2
504
55993
Y3
_
_
_
_
_
M
L
Y
F
S
L
F
W
A
A
Chimpanzee
Pan troglodytes
XP_509157
506
56077
Y3
_
_
_
_
_
M
L
Y
F
S
L
F
R
A
A
Rhesus Macaque
Macaca mulatta
XP_001115892
509
56717
Y3
_
_
_
_
_
M
L
Y
F
S
L
F
W
A
A
Dog
Lupus familis
XP_849244
505
56202
P3
_
_
_
_
_
M
L
P
F
S
L
L
W
A
T
Cat
Felis silvestris
Mouse
Mus musculus
P50431
478
52566
R4
_
_
_
_
M
A
D
R
D
A
T
L
W
A
S
Rat
Rattus norvegicus
NP_001008323
504
55746
P3
_
_
_
_
_
M
V
P
F
S
L
L
R
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510083
484
53208
N11
P
V
N
G
E
T
Q
N
V
K
L
W
E
S
H
Chicken
Gallus gallus
XP_414824
580
63427
A48
R
I
G
R
R
V
V
A
D
F
V
V
R
A
L
Frog
Xenopus laevis
NP_001087369
496
54903
T3
_
_
_
_
_
M
L
T
F
S
I
R
R
L
A
Zebra Danio
Brachydanio rerio
NP_001116846
492
54420
T3
_
_
_
_
_
M
L
T
L
T
L
R
Q
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P50432
507
55746
A3
_
_
_
_
_
M
F
A
R
I
V
S
R
R
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZJ5
517
57382
S11
A
M
A
L
R
R
L
S
S
S
I
D
K
P
I
Baker's Yeast
Sacchar. cerevisiae
P37291
469
52200
Y3
_
_
_
_
_
M
P
Y
T
L
S
D
A
H
H
Red Bread Mold
Neurospora crassa
P34898
480
52959
T3
_
_
_
_
_
M
S
T
Y
S
L
S
E
T
H
Conservation
Percent
Protein Identity:
100
98.8
94.1
95
N.A.
60.7
93.8
N.A.
60.5
54.1
80.9
76.1
N.A.
N.A.
N.A.
55.8
N.A.
Protein Similarity:
100
99
95.6
97.4
N.A.
74
96
N.A.
75.1
66.3
91.4
86.9
N.A.
N.A.
N.A.
73.1
N.A.
P-Site Identity:
100
90
100
70
N.A.
18.1
40
N.A.
6.6
6.6
50
30
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
90
100
70
N.A.
36.3
50
N.A.
26.6
40
60
40
N.A.
N.A.
N.A.
30
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.8
50.7
53.5
Protein Similarity:
N.A.
N.A.
N.A.
72.3
68.8
70.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
30
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
8
0
15
0
8
0
0
8
43
36
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
15
0
0
15
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
0
15
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
43
8
0
22
0
0
0
% F
% Gly:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
22
% H
% Ile:
0
8
0
0
0
0
0
0
0
8
15
0
0
8
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% K
% Leu:
0
0
0
8
0
0
50
0
8
8
58
22
0
8
8
% L
% Met:
0
8
0
0
8
72
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
8
15
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
0
8
15
8
0
8
8
0
0
15
36
8
0
% R
% Ser:
0
0
0
0
0
0
8
8
8
58
8
15
0
8
8
% S
% Thr:
0
0
0
0
0
8
0
22
8
8
8
0
0
15
22
% T
% Val:
0
8
0
0
0
8
15
0
8
0
15
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
29
0
0
% W
% Tyr:
0
0
0
0
0
0
0
29
8
0
0
0
0
0
0
% Y
% Spaces:
79
79
79
79
72
0
0
0
0
0
0
0
0
0
0
% _