KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHMT2
All Species:
26.97
Human Site:
T478
Identified Species:
45.64
UniProt:
P34897
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34897
NP_005403.2
504
55993
T478
F
L
L
K
D
S
E
T
S
Q
R
L
A
N
L
Chimpanzee
Pan troglodytes
XP_509157
506
56077
T478
F
L
L
K
D
S
E
T
S
Q
R
L
A
N
L
Rhesus Macaque
Macaca mulatta
XP_001115892
509
56717
T483
F
L
L
K
D
S
E
T
S
Q
R
L
A
D
L
Dog
Lupus familis
XP_849244
505
56202
T479
F
L
L
K
D
S
E
T
S
H
R
L
A
D
L
Cat
Felis silvestris
Mouse
Mus musculus
P50431
478
52566
D449
F
K
E
K
L
A
G
D
E
K
I
Q
S
A
V
Rat
Rattus norvegicus
NP_001008323
504
55746
T478
F
L
L
K
D
P
E
T
S
Q
R
L
A
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510083
484
53208
Y458
R
L
A
G
D
E
K
Y
Q
S
I
I
K
S
I
Chicken
Gallus gallus
XP_414824
580
63427
K548
T
L
K
E
F
K
E
K
L
E
E
E
K
Y
Q
Frog
Xenopus laevis
NP_001087369
496
54903
T470
F
L
L
E
D
Q
E
T
V
K
R
I
G
D
L
Zebra Danio
Brachydanio rerio
NP_001116846
492
54420
T466
F
L
L
E
D
A
E
T
V
S
R
I
A
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P50432
507
55746
F481
F
T
E
T
N
E
P
F
K
K
D
V
A
D
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZJ5
517
57382
I485
A
M
E
S
S
S
T
I
Q
S
E
I
A
K
L
Baker's Yeast
Sacchar. cerevisiae
P37291
469
52200
V450
K
V
D
E
G
S
D
V
L
N
T
W
K
K
E
Red Bread Mold
Neurospora crassa
P34898
480
52959
A443
N
K
Q
K
D
F
K
A
K
I
A
T
S
D
I
Conservation
Percent
Protein Identity:
100
98.8
94.1
95
N.A.
60.7
93.8
N.A.
60.5
54.1
80.9
76.1
N.A.
N.A.
N.A.
55.8
N.A.
Protein Similarity:
100
99
95.6
97.4
N.A.
74
96
N.A.
75.1
66.3
91.4
86.9
N.A.
N.A.
N.A.
73.1
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
13.3
93.3
N.A.
13.3
13.3
53.3
60
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
40
93.3
N.A.
40
26.6
80
86.6
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.8
50.7
53.5
Protein Similarity:
N.A.
N.A.
N.A.
72.3
68.8
70.4
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
15
0
8
0
0
8
0
58
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
65
0
8
8
0
0
8
0
0
43
0
% D
% Glu:
0
0
22
29
0
15
58
0
8
8
15
8
0
0
8
% E
% Phe:
65
0
0
0
8
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
8
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
8
15
29
0
0
15
% I
% Lys:
8
15
8
50
0
8
15
8
15
22
0
0
22
15
0
% K
% Leu:
0
65
50
0
8
0
0
0
15
0
0
36
0
0
65
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
8
0
0
0
22
0
% N
% Pro:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
8
0
0
15
29
0
8
0
0
8
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% R
% Ser:
0
0
0
8
8
43
0
0
36
22
0
0
15
8
0
% S
% Thr:
8
8
0
8
0
0
8
50
0
0
8
8
0
0
0
% T
% Val:
0
8
0
0
0
0
0
8
15
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _