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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHMT2
All Species:
38.48
Human Site:
S90
Identified Species:
65.13
UniProt:
P34897
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34897
NP_005403.2
504
55993
S90
A
A
L
E
A
L
G
S
C
L
N
N
K
Y
S
Chimpanzee
Pan troglodytes
XP_509157
506
56077
S90
A
A
L
E
A
L
G
S
C
L
N
N
K
Y
S
Rhesus Macaque
Macaca mulatta
XP_001115892
509
56717
S90
A
A
L
E
A
L
G
S
C
L
N
N
K
Y
S
Dog
Lupus familis
XP_849244
505
56202
S91
A
A
L
E
A
L
G
S
C
L
N
N
K
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
P50431
478
52566
G78
Y
P
G
Q
R
Y
Y
G
G
T
E
F
I
D
E
Rat
Rattus norvegicus
NP_001008323
504
55746
S90
A
A
L
E
A
L
G
S
C
L
N
N
K
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510083
484
53208
G84
Y
P
G
Q
R
Y
Y
G
G
T
E
F
V
D
E
Chicken
Gallus gallus
XP_414824
580
63427
S164
A
V
L
E
A
L
G
S
C
L
N
N
K
Y
S
Frog
Xenopus laevis
NP_001087369
496
54903
S82
A
A
L
E
A
L
G
S
C
L
N
N
K
Y
S
Zebra Danio
Brachydanio rerio
NP_001116846
492
54420
S79
A
A
L
E
A
Q
G
S
C
L
N
N
K
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P50432
507
55746
S93
A
V
M
D
A
L
G
S
A
M
C
N
K
Y
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZJ5
517
57382
S96
S
V
M
Q
A
V
G
S
V
M
T
N
K
Y
S
Baker's Yeast
Sacchar. cerevisiae
P37291
469
52200
N77
G
A
R
Y
Y
G
G
N
E
H
I
D
R
M
E
Red Bread Mold
Neurospora crassa
P34898
480
52959
N78
G
A
R
Y
Y
G
G
N
Q
H
I
D
E
I
E
Conservation
Percent
Protein Identity:
100
98.8
94.1
95
N.A.
60.7
93.8
N.A.
60.5
54.1
80.9
76.1
N.A.
N.A.
N.A.
55.8
N.A.
Protein Similarity:
100
99
95.6
97.4
N.A.
74
96
N.A.
75.1
66.3
91.4
86.9
N.A.
N.A.
N.A.
73.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
0
100
N.A.
0
93.3
100
93.3
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
100
100
100
100
N.A.
6.6
100
N.A.
6.6
93.3
100
93.3
N.A.
N.A.
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.8
50.7
53.5
Protein Similarity:
N.A.
N.A.
N.A.
72.3
68.8
70.4
P-Site Identity:
N.A.
N.A.
N.A.
46.6
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
80
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
65
65
0
0
72
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
58
0
8
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
15
0
15
0
% D
% Glu:
0
0
0
58
0
0
0
0
8
0
15
0
8
0
29
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% F
% Gly:
15
0
15
0
0
15
86
15
15
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
15
0
8
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
72
0
0
% K
% Leu:
0
0
58
0
0
58
0
0
0
58
0
0
0
0
0
% L
% Met:
0
0
15
0
0
0
0
0
0
15
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
58
72
0
0
0
% N
% Pro:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
22
0
8
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
15
0
15
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
0
0
0
0
0
72
0
0
0
0
0
0
72
% S
% Thr:
0
0
0
0
0
0
0
0
0
15
8
0
0
0
0
% T
% Val:
0
22
0
0
0
8
0
0
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
15
15
15
15
0
0
0
0
0
0
72
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _