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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHMT2
All Species:
0
Human Site:
S142
Identified Species:
0
UniProt:
P34897
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34897
NP_005403.2
504
55993
S142
G
V
N
V
Q
P
Y
S
G
S
P
A
N
L
A
Chimpanzee
Pan troglodytes
XP_509157
506
56077
Rhesus Macaque
Macaca mulatta
XP_001115892
509
56717
Dog
Lupus familis
XP_849244
505
56202
Cat
Felis silvestris
Mouse
Mus musculus
P50431
478
52566
Rat
Rattus norvegicus
NP_001008323
504
55746
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510083
484
53208
Chicken
Gallus gallus
XP_414824
580
63427
Frog
Xenopus laevis
NP_001087369
496
54903
Zebra Danio
Brachydanio rerio
NP_001116846
492
54420
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P50432
507
55746
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZJ5
517
57382
Baker's Yeast
Sacchar. cerevisiae
P37291
469
52200
Red Bread Mold
Neurospora crassa
P34898
480
52959
Conservation
Percent
Protein Identity:
100
98.8
94.1
95
N.A.
60.7
93.8
N.A.
60.5
54.1
80.9
76.1
N.A.
N.A.
N.A.
55.8
N.A.
Protein Similarity:
100
99
95.6
97.4
N.A.
74
96
N.A.
75.1
66.3
91.4
86.9
N.A.
N.A.
N.A.
73.1
N.A.
P-Site Identity:
100
0
0
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
0
0
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.8
50.7
53.5
Protein Similarity:
N.A.
N.A.
N.A.
72.3
68.8
70.4
P-Site Identity:
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
100
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
100
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
100
0
0
0
0
0
0
0
0
0
100
0
0
% N
% Pro:
0
0
0
0
0
100
0
0
0
0
100
0
0
0
0
% P
% Gln:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
100
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
100
0
100
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _