KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHMT1
All Species:
25.45
Human Site:
S17
Identified Species:
43.08
UniProt:
P34896
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P34896
NP_004160.3
483
53083
S17
K
D
A
D
L
W
S
S
H
D
K
M
L
A
Q
Chimpanzee
Pan troglodytes
XP_511325
483
53092
S17
K
D
A
D
L
W
S
S
H
D
K
M
L
A
Q
Rhesus Macaque
Macaca mulatta
XP_001096193
483
53122
S17
K
D
A
D
L
W
S
S
H
D
K
M
L
A
Q
Dog
Lupus familis
XP_851819
483
53313
L21
W
S
S
H
D
K
M
L
A
E
P
L
K
D
N
Cat
Felis silvestris
Mouse
Mus musculus
P50431
478
52566
S17
A
S
H
E
K
M
L
S
Q
P
L
K
D
S
D
Rat
Rattus norvegicus
NP_001041307
681
75356
S214
R
D
A
T
V
W
A
S
H
E
K
M
L
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510083
484
53208
S17
Q
N
V
K
L
W
E
S
H
S
N
M
L
V
Q
Chicken
Gallus gallus
XP_414824
580
63427
S114
P
S
A
E
L
W
A
S
H
S
K
M
L
L
E
Frog
Xenopus laevis
NP_001080356
485
53733
S18
T
L
Q
E
T
W
E
S
H
N
K
M
V
L
E
Zebra Danio
Brachydanio rerio
NP_957340
481
53365
K17
K
T
W
E
S
H
N
K
M
M
L
E
P
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P50432
507
55746
N43
V
Q
R
H
K
Y
T
N
N
E
N
I
L
V
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZJ5
517
57382
T46
E
K
E
R
S
R
V
T
W
P
K
Q
L
N
A
Baker's Yeast
Sacchar. cerevisiae
P37291
469
52200
L17
H
K
L
I
T
S
H
L
V
D
T
D
P
E
V
Red Bread Mold
Neurospora crassa
P34898
480
52959
S17
H
K
A
M
L
E
H
S
L
V
E
S
D
P
Q
Conservation
Percent
Protein Identity:
100
99.7
98.1
91.3
N.A.
90.2
65
N.A.
87.5
67.9
78.9
78.8
N.A.
N.A.
N.A.
57.9
N.A.
Protein Similarity:
100
99.7
98.5
96
N.A.
94.1
68.1
N.A.
94
75.3
87.2
88.8
N.A.
N.A.
N.A.
73.1
N.A.
P-Site Identity:
100
100
100
0
N.A.
6.6
60
N.A.
46.6
53.3
33.3
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
20
N.A.
20
86.6
N.A.
60
73.3
60
20
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
54.7
53.6
56.9
Protein Similarity:
N.A.
N.A.
N.A.
70.6
72.4
73
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
43
0
0
0
15
0
8
0
0
0
0
22
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
29
0
22
8
0
0
0
0
29
0
8
15
8
15
% D
% Glu:
8
0
8
29
0
8
15
0
0
22
8
8
0
8
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
15
0
8
15
0
8
15
0
50
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
29
22
0
8
15
8
0
8
0
0
50
8
8
0
0
% K
% Leu:
0
8
8
0
43
0
8
15
8
0
15
8
58
22
0
% L
% Met:
0
0
0
8
0
8
8
0
8
8
0
50
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
8
8
8
15
0
0
8
8
% N
% Pro:
8
0
0
0
0
0
0
0
0
15
8
0
15
8
0
% P
% Gln:
8
8
8
0
0
0
0
0
8
0
0
8
0
0
43
% Q
% Arg:
8
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
22
8
0
15
8
22
65
0
15
0
8
0
8
8
% S
% Thr:
8
8
0
8
15
0
8
8
0
0
8
0
0
8
0
% T
% Val:
8
0
8
0
8
0
8
0
8
8
0
0
8
15
8
% V
% Trp:
8
0
8
0
0
50
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _