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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP2C18 All Species: 16.36
Human Site: S23 Identified Species: 60
UniProt: P33260 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P33260 NP_000763.1 490 55711 S23 L L S L W R Q S S G R G R L P
Chimpanzee Pan troglodytes XP_001152531 490 55771 S23 L L S L W S Q S S G R G R L L
Rhesus Macaque Macaca mulatta Q6GUQ4 493 56626 V26 L V S I W R Q V H S S W N L P
Dog Lupus familis XP_534973 490 55872 N23 S F F L W N Q N R A K G K L P
Cat Felis silvestris
Mouse Mus musculus Q64458 490 55711 S23 L L S L W R Q S S G R G K L P
Rat Rattus norvegicus P33273 490 55972 S23 L L S L W R Q S S G R G K L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P20678 491 56467 T26 L I A A W R S T S Q R G K E P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.4 57.2 69.3 N.A. 76.5 77.9 N.A. N.A. 57.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 92.4 75.2 84.2 N.A. 88.9 90 N.A. N.A. 74.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 46.6 40 N.A. 93.3 93.3 N.A. N.A. 46.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 60 60 N.A. 100 100 N.A. N.A. 73.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 15 0 0 0 0 0 15 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % E
% Phe: 0 15 15 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 58 0 86 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % H
% Ile: 0 15 0 15 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 15 0 58 0 0 % K
% Leu: 86 58 0 72 0 0 0 0 0 0 0 0 0 86 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 15 0 15 0 0 0 0 15 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86 % P
% Gln: 0 0 0 0 0 0 86 0 0 15 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 72 0 0 15 0 72 0 29 0 0 % R
% Ser: 15 0 72 0 0 15 15 58 72 15 15 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % T
% Val: 0 15 0 0 0 0 0 15 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 100 0 0 0 0 0 0 15 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _